Association of pre-diabetes with increased obesity and depression in older male and female: A secondary analysis of the Korea National Health and Nutrition Examination Survey 2020.

Purpose: This study aimed to investigate the association among pre-diabetes, increased obesity, and depression in Korean older male and female. Methods: Data of 1,005 participants (≥65 years) were extracted from the Korea National Health and Nutrition Examination Survey (KNHANES) VIII-2, 2020. A complex sampling design was adopted to reflect stratification, clustering, and weights. Data were analyzed using t-test, Rao-Scott chi-square test, and simple and multiple logistic regression. In predicting the risk factors for pre-diabetes, after adjusting, multiple logistic regression analysis was performed to confirm the relative contribution of each predictor variable. Results: Body mass index, waist circumference (WC), and incidence of depression were higher in the pre-diabetes group than in the normal group. According to the simple logistic regression analyses, in male, the odds ratio (OR) of pre-diabetes increased by 1.73, 2.25, and 2.53 for obesity (25.0~29.9 kg/m Conclusion: This study provides evidence that interventions for obesity and depression should be included differently in pre-diabetes management programs for older male and female.