Evidence map›Paper›PMID 41584843›Full record

ArticleFrontiers in cell and developmental biology2025

Dynamic crosstalk between Tspan4

Siyu Zhang, Mengci Wang, Abudurexiti Kutibiding, Dandan Liu, Tuersunnayi Manafu, Wen Zhao, Yi Yang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cell and developmental biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Siyu Zhang *Department of Spinal Minimally Invasive and Precision Orthopedics, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, China.
Mengci Wang *Department of Histology and Embryology, School of Basic Medical Sciences, Xinjiang Medical University, Urumqi, China.
Abudurexiti KutibidingDepartment of Spinal Minimally Invasive and Precision Orthopedics, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, China.
Dandan LiuDepartment of Spinal Minimally Invasive and Precision Orthopedics, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, China.
Tuersunnayi ManafuDepartment of Spinal Minimally Invasive and Precision Orthopedics, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, China.
Wen ZhaoDepartment of Spinal Minimally Invasive and Precision Orthopedics, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, China.
Yi YangDepartment of Spinal Minimally Invasive and Precision Orthopedics, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The cell - cell communication between macrophages and mesenchymal stromal/stem cells (MSCs) holds pivotal importance in the fracture healing process. Considering the intricate nature of the Methods: Single - cell sequencing was utilized to analyze the expression of Tspan4 Results: Through single - cell sequencing, it was ascertained that macrophages highly expressed Tspan4 during the fracture healing process and could be categorized into Tspan4

Indexed as

AMPKbone marrow mesenchymal stem cellsfracture healingIL1bmacrophagesmigrasomes

Identifiers

PMID41584843
PMCPMC12827626

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.