Evidence map›Paper›PMID 41584786›Full record

ArticleUrology case reports2026

Pathway from lichen sclerosus to squamous cell carcinoma of the penis: the oncologist's perspective.

Marisa Couto, Maria João Oura, Nuno Teixeira Tavares, Miguel Barbosa, Pedro Pereira, Rui Pinto, Isabel Augusto

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Urology case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Marisa CoutoServiço de Oncologia Médica, Unidade Local de Saúde São João, Porto, Portugal.
Maria João OuraServiço de Oncologia Médica, Unidade Local de Saúde São João, Porto, Portugal.
Nuno Teixeira TavaresServiço de Oncologia Médica, Unidade Local de Saúde São João, Porto, Portugal.
Miguel BarbosaServiço de Oncologia Médica, Unidade Local de Saúde São João, Porto, Portugal.
Pedro PereiraServiço de Anatomia Patológica, Unidade Local de Saúde São João, Porto, Portugal.
Rui PintoServiço de Urologia, Unidade Local de Saúde São João, Porto, Portugal.
Isabel AugustoServiço de Oncologia Médica, Unidade Local de Saúde São João, Porto, Portugal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Male genital lichen sclerosus (LS) is a chronic inflammatory disorder with malignant potential, transforming into penile squamous cell carcinoma (SCC) in up to 30 % of cases. We report a 59-year-old man diagnosed with LS in 2008 after circumcision, without follow-up. Sixteen years later, he developed a suspicious induration of the balanopreputial sulcus. Partial penectomy and lymphadenectomy revealed a pT2N3 SCC with adjacent LS. Rapid local recurrence required total penile amputation, followed by adjuvant chemotherapy. This case underscores the strong LS-SCC association and the need for early recognition, continuous surveillance, and timely multidisciplinary management to prevent delayed diagnosis and radical surgery.

Indexed as

Lichen sclerosusPenile cancerSquamous cell carcinoma

Identifiers

PMID41584786
PMCPMC12828411

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.