Evidence map›Paper›PMID 41584730›Full record

ArticleEndoscopy international open2026

Endoscopic submucosal dissection for early gastric cancer in the elderly: Spanish multicenter prospective study during initial experience.

Maria Moreno-Sanchez, Alberto Herreros de Tejada, Glòria Fernández-Esparrach, Unai Goikoetxea, Enrique Rodriguez de Santiago, Eduardo Albéniz, Joaquin Rodriguez Sánchez, Pablo Miranda Garcia, Oscar Nogales, Hugo Uchima and 4 more

Abstract read
In one paragraph

Article in Endoscopy international open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Maria Moreno-SanchezGastroenterology, 12 de Octubre University Hospital, Madrid, Spain.ORCID 0000-0002-7909-0584
Alberto Herreros de TejadaGastroenterology, Puerta de Hierro University Hospital of Majadahonda, Majadahonda, Spain.
Glòria Fernández-EsparrachEndoscopy Unit, Institut de Malalties Digestives i Metabòliques, Hospital Clinic, Barcelona, Spain.ORCID 0000-0002-3378-3940
Unai GoikoetxeaUniversity Hospital of Donostia, Donostia, Spain.
Enrique Rodriguez de SantiagoGastroenterology and Hepatology, Hospital Universitario Ramón y Cajal, Universidad de Alcalá, IRYCIS, Madrid, Spain.ORCID 0000-0002-2852-6042
Eduardo AlbénizGastroenterology, Endoscopy Unit, Hospital Universitario de Navarra (HUN), Pamplona, Spain.ORCID 0000-0002-9311-3746
Joaquin Rodriguez Sánchez12 de Octubre University Hospital, Madrid, Spain.
Pablo Miranda GarciaGastroenterology, Hospital Universitario de la Princesa, Madrid, Spain.
Oscar NogalesGeneral University Hospital Gregorio Maranon, Madrid, Spain.
Hugo UchimaEndoscopy Unit, Hospital Universitari Germans Trias i Pujol, Badalona, Spain.ORCID 0000-0001-8411-4993
Alvaro TeránServicio de Gastroenterologia, Hospital Universitario Marqués de Valdecilla, Santander, Spain.
David Lora-Pablos12 de Octubre University Hospital, Madrid, Spain.
Jose Diaz TasendeGastroenterology, 12 de Octubre University Hospital, Madrid, Spain.
José C Marín-GabrielGastroenterology, 12 de Octubre University Hospital, Madrid, Spain.ORCID 0000-0002-4270-8790

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and study aims: Data on survival for elderly Western patients undergoing endoscopic submucosal dissection (ESD) for early gastric cancer (EGC) are scarce. Patients and methods: A multicenter, prospective, cohort study (2016-2022) was conducted in 26 Spanish hospitals that included patients aged > 70 years treated with ESD for EGC. The primary endpoint was overall survival in octogenarians compared with the previous decade; secondary outcomes included safety and technical success. Results: A total of 217 patients were included, 135 in their 70s (Group A) and 82 in their 80s (Group B). Group B had higher comorbidity (73.2% vs 46.7%; Conclusions: Octogenarians with EGC benefit from ESD in a Western setting in terms of disease-free survival, but have lower long-term survival due to comorbidities, underscoring the importance of pre-procedure risk assessment. ESD is a proven safe technique, but in the subgroup of patients aged ≥ 80 years with severe comorbidities (ASA-PS ≥ IV), periprocedural mortality is increased and the indication should be carefully evaluated.

Indexed as

Endoscopic resection (ESD, EMRc, ...)Endoscopy Upper GI TractPerformance and complicationsPrecancerous conditions & cancerous lesions (displasia and cancer) stomachQuality and logistical aspects

Identifiers

PMID41584730
PMCPMC12828969

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.