Evidence map›Paper›PMID 41584725›Full record

ArticleHuman mutation2026

Revealing the Action Mechanism of Exogenous Hydrogen Sulfide Intervention in Colorectal Cancer Pathogenesis Based on Multiomics Analysis and Experimental Validation.

Facai Cui, Chen Yu, Weifeng Zhao, Juan Shi, Yang Liu, Fengzhen Liu, Sujit Nair

Abstract read
In one paragraph

Article in Human mutation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Facai CuiDepartment of Clinical Laboratory, Henan Provincial People's Hospital, Zhengzhou, Henan, China, hnsrmyy.net.ORCID https://orcid.org/0009-0005-7858-6456
Chen YuDepartment of Pathology, Henan Cancer Hospital, Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou, Henan, China, zzu.edu.cn.ORCID https://orcid.org/0009-0008-1064-0606
Weifeng ZhaoDepartment of Oncology Laboratory, Henan Provincial People's Hospital, Zhengzhou, Henan, China, hnsrmyy.net.ORCID https://orcid.org/0009-0002-5568-3702
Juan ShiDepartment of Clinical Laboratory, Henan Provincial People's Hospital, Zhengzhou, Henan, China, hnsrmyy.net.ORCID https://orcid.org/0009-0002-9658-4831
Yang LiuDepartment of Clinical Laboratory, Henan Provincial People's Hospital, Zhengzhou, Henan, China, hnsrmyy.net.ORCID https://orcid.org/0009-0000-9710-2107
Fengzhen LiuDepartment of Clinical Laboratory, Henan Provincial People's Hospital, Zhengzhou, Henan, China, hnsrmyy.net.ORCID https://orcid.org/0009-0007-4317-3613
Sujit NairDepartment of Clinical Laboratory, Henan Provincial People's Hospital, Zhengzhou, Henan, China, hnsrmyy.net.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Colorectal cancer (CRC) ranks among the leading causes of cancer-related mortality worldwide. Hydrogen sulfide (H

Indexed as

Colorectal NeoplasmsHydrogen SulfideBiomarkers, TumorCell Line, TumorCell ProliferationComputational BiologyGene Expression ProfilingGene Expression Regulation, NeoplasticGene Regulatory NetworksHumansMultiomicsPrognosisSignal TransductionBiomarkers, TumorHydrogen Sulfidecolorectal cancerhydrogen sulfidemultiomics analysispathogenesis risktherapeutic mechanism

Identifiers

PMID41584725
PMCPMC12829476

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.