Evidence map›Paper›PMID 41584460›Full record

ArticleStroke (Hoboken, N.J.)2021

Mechanical Thrombectomy of the Fetal Posterior Cerebral Artery.

Mohamad Abdalkader, Anurag Sahoo, Adam A Dmytriw, Waleed Brinjikji, Guilherme Dabus, Eytan Raz, Leonardo Renieri, Antonio Laiso, Alberto Maud, Mario Martínez-Galdámez and 14 more

Abstract read
In one paragraph

Article in Stroke (Hoboken, N.J.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. A review of acute ischemic stroke caused by distal, medium vessel occlusions.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025
    Review
  3. Basilar artery occlusion management: An international survey of middle versus high-income countries.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2024
    Article
  4. Endovascular Treatment for Basilar Artery Occlusion.Journal of clinical medicine · 2024
    Review
  5. Observational
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Mohamad AbdalkaderDepartment of Radiology Boston Medical Center Boston University-School of Medicine Boston MA.ORCID https://orcid.org/0000-0002-9528-301X
Anurag SahooDepartment of Neurology, Boston Medical Center Boston University-School of Medicine Boston MA.
Adam A DmytriwNeuroendovascular Program Massachusetts General Hospital - Harvard Medical School Boston MA.
Waleed BrinjikjiDepartment of Radiology, Mayo Clinic Rochester MN.
Guilherme DabusInterventional Neuroradiology Miami Cardiac & Vascular Institute and Baptist Neuroscience Center Miami FL.
Eytan RazDepartment of Radiology New York University Langone Medical Center New York NY.
Leonardo RenieriInterventional Neuroradiology Unit University Hospital Careggi Firenze Toscana Italy.
Antonio LaisoInterventional Neuroradiology Unit University Hospital Careggi Firenze Toscana Italy.
Alberto MaudDepartment of Neurology Texas Tech University Health Sciences Center El Paso El Paso TX.
Mario Martínez-GaldámezInterventional Neuroradiology/Endovascular Neurosurgery Hospital Clínico Universitario de Valladolid Valladolid Spain.ORCID https://orcid.org/0000-0002-8024-4712
Jorge Galván-FernándezInterventional Neuroradiology/Endovascular Neurosurgery Hospital Clínico Universitario de Valladolid Valladolid Spain.
Miguel Schüller-ArteagaInterventional Neuroradiology/Endovascular Neurosurgery Hospital Clínico Universitario de Valladolid Valladolid Spain.
Fawaz Al-MuftiDepartment of Neurosurgery Westchester Medical Center at New York Medical College Valhalla NY.
Krishna AmuluruDivision of Interventional Neuroradiology Goodman Campbell Brain and Spine, Ascension St. Vincent Medical Center Indianapolis IN.
Johanna T FifiDepartment of Neurosurgery Icahn School of Medicine at Mount Sinai New York NY.
Shahram MajidiDepartment of Neurosurgery Icahn School of Medicine at Mount Sinai New York NY.
Priyank KhandelwalDepartment of Neurosurgery Rutgers University Newark NJ.
Justin M MooreDivision of Neurosurgery Beth Israel Deaconess Medical Center Boston MA.
Santiago Ortega-GutierrezDepartment of Neurology, Radiology and Neurosurgery The University of Iowa Hospitals and Clinics Iowa City IA.
Ameer E HassanDepartment of Neurology University of Texas Rio Grande Valley, Valley Baptist Medical Center Harlingen TX.
James E SieglerCooper Neurological Institute Cooper University Hospital Camden NJ.
Simon NagelDepartment of Neurology University Hospital Heidelberg Heidelberg Germany.
Osama O ZaidatNeuroscience Institute St Vincent Mercy Hospital Toledo OH.
Thanh N NguyenDepartment of Radiology Boston Medical Center Boston University-School of Medicine Boston MA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Fetal posterior cerebral artery (FPCA) occlusion is a rare but potentially disabling cause of stroke. While endovascular treatment is established for acute large vessel occlusion stroke, FPCA occlusions were excluded from acute ischemic stroke trials. We aim to report the feasibility, safety, and outcome of mechanical thrombectomy in acute FPCA occlusions. Methods: We performed a multicenter retrospective review of consecutive patients who underwent mechanical thrombectomy of acute FPCA occlusion. Primary FPCA occlusion was defined as an occlusion that was identified on the pre-procedure computed tomography angiography or baseline angiogram whereas a secondary FPCA occlusion was defined as an occlusion that occurred secondary to embolization to a new territory after recanalization of a different large vessel occlusion. Demographics, clinical presentation, imaging findings, endovascular treatment, and outcome were reviewed. Results: There were 25 patients with acute FPCA occlusion who underwent mechanical thrombectomy, distributed across 14 centers. Median National Institutes of Health Stroke Scale on presentation was 16. There were 76% (19/25) of patients who presented with primary FPCA occlusion and 24% (6/25) of patients who had a secondary FPCA occlusion. The configuration of the FPCA was full in 64% patients and partial or "fetal-type" in 36% of patients. FPCA occlusion was missed on initial computed tomography angiography in 21% of patients with primary FPCA occlusion (4/19). The site of occlusion was posterior communicating artery in 52%, P2 segment in 40% and P3 in 8% of patients. Thrombolysis in cerebral infarction 2b/3 reperfusion was achieved in 96% of FPCA patients. There were no intraprocedural complications. At 90 days, 48% (12/25) were functionally independent as defined by modified Rankin scale≤2. Conclusions: Endovascular treatment of acute FPCA occlusion is safe and technically feasible. A high index of suspicion is important to detect occlusion of the FPCA in patients presenting with anterior circulation stroke syndrome and patent anterior circulation. Novelty and significance: This is the first multicenter study showing that thrombectomy of FPCA occlusion is feasible and safe.

Indexed as

acute strokefetal posterior cerebral arterymechanical thrombectomy

Identifiers

PMID41584460
PMCPMC12512354

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.