Evidence map›Paper›PMID 41584396›Full record

ArticleClinical case reports2026

Non-Operable Squamous Cell Carcinoma of the Infraorbital Region Treated With Electrochemotherapy: A Case Report.

Gianluca Nicolai, Francesco Campanella, Sergio Alexandre Gehrke, Antonio Scarano

Abstract read
In one paragraph

Article in Clinical case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Gianluca NicolaiDepartment of Maxillo-Facial Surgery University of Tor Vergata Rome Italy.
Francesco CampanellaDepartment of Maxillo-Facial Surgery University of Tor Vergata Rome Italy.
Sergio Alexandre GehrkeDepartment of Biotechnology Universidad Católica de Murcia (UCAM) Murcia Spain.
Antonio ScaranoDepartment of Innovative Technologies in Medicine & Dentistry University of Chieti-Pescara Chieti Italy.ORCID https://orcid.org/0000-0003-1374-6146

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cutaneous squamous cell carcinoma (cSCC) is a malignant epithelial tumor of the skin, classified as a nonmelanoma skin cancer. It may develop from precancerous conditions such as chronic inflammatory dermatoses, actinic keratosis, or actinic cheilitis, but can also arise de novo. The aim of this case report is to describe the clinical management and therapeutic outcome of a patient with infraorbital squamous cell carcinoma who was deemed inoperable due to poor general health conditions, and was therefore treated with electrochemotherapy (ECT) as an alternative local therapy. A 73-year-old male patient with a complex medical history, including untreated chronic kidney disease, untreated diabetes mellitus, left leg lymphedema, right leg thrombosis, previous lobectomy for lung cancer, and amputation of the left big toe due to squamous cell carcinoma (SCC), presented with a new lesion diagnosed as SCC located in the infraorbital region. Electrochemotherapy is a minimally invasive oncologic treatment that combines electroporation with the administration of chemotherapeutic agents to enhance their cytotoxic efficacy. Bleomycin, 15 μ/m

Indexed as

bleomycinelectrochemotherapyintralesionalnon‐melanoma skin cancersquamous cell carcinoma

Identifiers

PMID41584396
PMCPMC12828063

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.