Evidence map›Paper›PMID 41584392›Full record

ArticleClinical case reports2026

Initially Normal MRI, Delayed Splenial Lesion in Marchiafava-Bignami Disease.

Tsuyoshi Nojima, Ryo Tanabe, Takafumi Obara, Takashi Hongo, Tetsuya Yumoto

Abstract read
In one paragraph

Article in Clinical case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Tsuyoshi NojimaDepartment of Emergency, Critical Care, and Disaster Medicine, Faculty of Medicine Dentistry and Pharmaceutical Sciences, Okayama University Okayama Okayama Prefecture Japan.ORCID https://orcid.org/0000-0003-0768-0179
Ryo TanabeDepartment of Emergency, Critical Care, and Disaster Medicine, Faculty of Medicine Dentistry and Pharmaceutical Sciences, Okayama University Okayama Okayama Prefecture Japan.
Takafumi ObaraDepartment of Emergency, Critical Care, and Disaster Medicine, Faculty of Medicine Dentistry and Pharmaceutical Sciences, Okayama University Okayama Okayama Prefecture Japan.
Takashi HongoDepartment of Emergency, Critical Care, and Disaster Medicine, Faculty of Medicine Dentistry and Pharmaceutical Sciences, Okayama University Okayama Okayama Prefecture Japan.ORCID https://orcid.org/0000-0002-1655-2294
Tetsuya YumotoDepartment of Emergency, Critical Care, and Disaster Medicine, Faculty of Medicine Dentistry and Pharmaceutical Sciences, Okayama University Okayama Okayama Prefecture Japan.ORCID https://orcid.org/0000-0003-1766-8026

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Marchiafava-Bignami disease (MBD) may show normal findings on early MRI. In patients with alcohol use disorder or risk of thiamine deficiency, repeat imaging is important because splenial lesions can develop later. Recognizing this pattern is key to avoiding delayed diagnosis.

Indexed as

alcoholMarchiafava–Bignami diseaseMRIthiamine

Identifiers

PMID41584392
PMCPMC12826988

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.