ArticleActa stomatologica Croatica2025
Cross-Sectional Analysis of Matrix Metalloproteinases and Bone Resorption Regulators in Apical Periodontitis: Linking Molecular Mechanisms with Clinical and Histopathological Features.
Article in Acta stomatologica Croatica, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objectives: (a) To quantify the relative gene expression of matrix metalloproteinases (MMP) Materials and Methods: The study cohort comprised 80 AP lesions obtained from 80 adult volunteers during apicoectomy procedures. The healthy control cohort consisted of 50 dental pulp samples from intact teeth extracted for orthodontic purposes, collected from 50 voluntary donors. Relative gene expression of Results: Higher gene expression levels of Conclusions: Concurrent overexpression of the studied mediators, along with their positive correlations in AP lesions, indicates their coordinated role in disease progression and alveolar bone resorption.
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