ArticleNeurosurgery practice2026
Outcomes of Microsurgical Treatment for Unruptured Intracranial Aneurysms: A 7-Year Institutional Review.
Article in Neurosurgery practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Outcomes of Microsurgical Treatment for Unruptured Intracranial Aneurysms: A 7-Year Institutional Review.Neurosurgery practice · 2026Article
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Authors and funding
16 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
objectivesThe optimal management of unruptured intracranial aneurysms (UIAs) remains controversial. Options include observation, endovascular treatment, microsurgical intervention, or a combination. However, clear outcome data for UIA treatment remain elusive. This study analyzed UIA treatment outcomes at a quaternary center and explored factors associated with poor neurological outcomes.
methodsAll records of patients treated for UIA from 2014 through 2020 were retrospectively reviewed. Inclusion criteria were availability of treatment data, adequate follow-up, and a modified Rankin Scale (mRS) score of ≤2 at admission. Outcomes analyzed included 1-year mRS scores, with a poor neurological outcome defined as an mRS score of >2. Multivariate logistic regression analysis included variables with
resultsA total of 390 patients met the inclusion criteria (294 [75.4%] women, 96 [24.6%] men). Forty-one (10.5%) had previous aneurysmal subarachnoid hemorrhages (SAHs). The mean (SD) population, hypertension, age, size of aneurysm, earlier SAH from another aneurysm, site of aneurysm (PHASES) score was 4.5 (2.7). Thirty-eight patients (9.7%) had mRS scores >2 at the 1-year follow-up. Of 555 UIAs, 388 (69.9%) were saccular and 77 (13.9%) were in the posterior circulation. Multivariate analysis showed that no tobacco use (odds ratio [OR] 4.35, 95% CI: 1.72-12.5,
conclusionMicrosurgical treatment of UIAs is associated with low rates of residual aneurysms, retreatment, and poor neurological outcomes. Risk factors for a poor neurological outcome included no history of tobacco use, presence of diabetes mellitus, hyperlipidemia, and a high PHASES score. These findings refute the potential value of treating patients with low PHASES scores.
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