ArticleKidney international reports2026
Tailored Kidney Stone Prevention Improves Metabolic Risk Factors and Reduces Renal Colic Rate.
Article in Kidney international reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Introduction: There is limited real-world data on the effectiveness of combined prophylactic measures to prevent recurrent kidney stone formation. Methods: This single-center retrospective study evaluated the effect of combined, patient-tailored prophylaxis on metabolic risk factors, urinary crystallization risk indices, and renal colic and urological intervention rates in a real-life clinical setting. Results: Four hundred ninety patients with nephrolithiasis (NL) with a median follow-up of 12.8 months were evaluated. After the introduction of prophylaxis, the main metabolic risk factors, namely urinary volume, oxalate, calcium, and citrate excretion improved significantly in patients presenting the specific risk factor at baseline (+ 653 ml/24 h for urinary volume, - 10.9 mg/24 h for oxaluria, - 2.35 mmol/24 h for calciuria, and + 901 μmol/24 h for citraturia; all Conclusion: Combined, patient-tailored prophylaxis in kidney stone formers significantly improves metabolic risk factors and urinary crystallization risk indices, resulting in a significant reduction of renal colic and urological intervention rates.
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