ArticleJournal of oral biology and craniofacial research
Comparison of ozone therapy and antimicrobial photodynamic therapy in periodontitis: A randomized clinical trial.
Article in Journal of oral biology and craniofacial research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07551297 (The Effect of Adjunctive Ozone Therapy on Clinical Outcomes Following Open Flap Debridement in Patients With Stage III Periodontitis), which is not on this map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Effect of Adjunctive Ozone Therapy on Clinical Outcomes Following Open Flap Debridement in Patients With Stage III Periodontitis: A Randomized Split-Mouth Clinical Trial
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Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: This randomized clinical trial evaluated the comparative efficacy of ozone therapy and ICG-mediated antimicrobial photodynamic therapy as adjunctive to scaling and root planing in the management of periodontitis, by assessing clinical outcomes, inflammatory biomarkers, specifically interleukin-1β (IL-1β) and Pentraxin-3 (PTX-3), and microbial load via quantitative PCR. Methods: This is a parallel-arm, single-blinded, randomized controlled trial that included 36 patients with Stage III Grade B periodontitis, allocated randomly to three groups. Group 1 {Scaling and Root planing (SRP)}, Group 2 {SRP + Ozone Therapy (OT}), and Group 3 {SRP + Antimicrobial Photodynamic Therapy (aPDT)}. Clinical parameters, biochemical markers, and microbial count were recorded at baseline, 1 month, and 3 months. Result: The change in Plaque Index (PI), Gingival Index (GI), Probing Pocket Depth (PPD), and Clinical Attachment Level (CAL) from baseline to 1 month and from baseline to 3 months was significantly higher in the SRP + OT group ( Conclusion: All treatment modalities resulted in significant improvements in all the parameters over time. However, SRP + Ozone Therapy consistently achieved the improvement across all parameters, when compared to SRP alone or SRP with aPDT.
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