Evidence map›Paper›PMID 41584003›Full record

ArticleStroke (Hoboken, N.J.)2022

Current Opinions on Optimal Management of Basilar Artery Occlusion: After the BEST of BASICS Survey.

Brian Drumm, Soma Banerjee, Muhammad M Qureshi, Wouter J Schonewille, Piers Klein, Xiaochuan Huo, Yimin Chen, Daniel Strbian, Urs Fischer, Volker Puetz and 38 more

Abstract read
In one paragraph

Article in Stroke (Hoboken, N.J.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Basilar artery occlusion management: An international survey of middle versus high-income countries.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2024
    Article
  5. Article
  6. Endovascular Treatment for Basilar Artery Occlusion.Journal of clinical medicine · 2024
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Evolution of endovascular therapy trials for basilar artery occlusion.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2023
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

48 authors.

Brian DrummStroke Medicine Imperial College Healthcare NHS Trust, Charing Cross Hospital London UK.
Soma BanerjeeStroke Medicine Imperial College Healthcare NHS Trust, Charing Cross Hospital London UK.
Muhammad M QureshiDepartment of Radiology, Neurology Boston Medical Center Boston University School of Medicine Boston MA United States.
Wouter J SchonewilleDepartment of Neurology St. Antonius Hospital Nieuwegein The Netherlands.
Piers KleinDepartment of Radiology, Neurology Boston Medical Center Boston University School of Medicine Boston MA United States.
Xiaochuan HuoInterventional Neuroradiology Beijing Tiantan Hospital Beijing China.
Yimin ChenDepartment of Neurology Foshan Sanshui District People's Hospital Foshan Guangdong Province China.
Daniel StrbianDepartment of Neurology Helsinki University Hospital Helsinki Finland.
Urs FischerDepartment of Neurology Stroke Research Center Bern Bern University Hospital University of Bern Bern Switzerland.
Volker PuetzDepartment of Neurology University Hospital Carl Gustav Carus Technische Universität Dresden Dresden Germany.
Wei HuThe First Affiliated Hospital of USTC Division of Life Sciences and Medicine China.
Xunming JiXuanwu Hospital Beijing China.
Chuanhui LiXuanwu Hospital Beijing China.
Fana AlemsegedMedicine and Neurology Melbourne Brain Centre at the Royal Melbourne Hospital University of Melbourne Parkville Victoria Australia.
Hiroshi YamagamiStroke Neurology National Hospital Organization Osaka National Hospital Osaka Japan.
Simona SaccoNeuroscience Section Department of Biotechnological and Applied Clinical Sciences University of L'Aquila L'Aquila AQ Italy.
Gustavo SaposnikStroke Outcomes and Decision Neuroscience Research Unit Division of Neurology University of Toronto Toronto Canada.
Patrik MichelNeurology Service Clinical Neurosciences Lausanne University Hospital and University of Lausanne Lausanne Switzerland.
Espen Saxhaug KristoffersenDepartment of Neurology Akershus University Hospital Lørenskog and Department of General Practice University of Oslo Oslo Norway.
Petra SedovaDepartment of Neurology International Clinical Research Center St. Anne's University Hospital and Faculty of Medicine Masaryk University Brno Czech Republic.
Robert MikulikDepartment of Neurology International Clinical Research Center St. Anne's University Hospital and Faculty of Medicine Masaryk University Brno Czech Republic.
James E SieglerCooper Neurological Institute Cooper University Hospital Camden NJ United States.
Thomas R MeinelDepartment of Neurology Stroke Research Center Bern Bern University Hospital University of Bern Bern Switzerland.
Diana Aguiar de SousaStroke Center Centro Hospitalar Universitário Lisboa Central - CHULC Portugal CEEM and Institute of Anatomy Faculdade de Medicina Universidade de Lisboa Lisbon Portugal.
Kyriakos LobotesisRadiology Imperial College Healthcare NHS Trust Charing Cross Hospital London UK.
Dylan RoiRadiology Imperial College Healthcare NHS Trust Charing Cross Hospital London UK.
Jelle DemeestereDepartment of Neurology Leuven University Hospital Leuven Belgium.
Kaiz S AsifAmita Health and University of Illinois-Chicago Chicago IL United States.
Sheila O MartinsNeurology Federal University of Rio Grande do Sul Porto Alegre Hospital de Clínicas de Porto Alegre Porto Alegre Brazil.
Mohamad AbdalkaderDepartment of Radiology, Neurology Boston Medical Center Boston University School of Medicine Boston MA United States.
Mayank GoyalDepartment of Radiology University of Calgary Alberta Canada.
Thang Huy NguyenCerebrovascular Disease 115 People Hospital Ho Chi Minh City Vietnam.
Mai Duy TonStroke Center Bach Mai Hospital Hanoi Medical University, Vietnam National University Hanoi Vietnam.
Yuyou ZhuThe First Affiliated Hospital of USTC Division of Life Sciences and Medicine China.
Xinfeng LiuStroke Center Neurology The First Affiliated Hospital of USTC Division of Life Sciences and Medicine University of Science and Technology of China Hefei China.
Zhongming QiuXinqiao Hospital and The Second Affiliated Hospital Army Medical University Chongqing China.
Zhongrong MiaoInterventional Neuroradiology Beijing Tiantan Hospital Beijing China.
Jildaz CaroffDepartment of Interventional Neuroradiology NEURI Brain Vascular Center Bicêtre Hospital Assistance Publique Hôpitaux de Paris Le Kremlin-Bicêtre France.
Michele RomoliNeurology and Stroke Unit Department of Neuroscience Bufalini Hospital Cesena Italy.
Francesco DianaDepartment of Neuroradiology University Hospital 'San Giovanni di Dio e Ruggi d'Aragona' Campania Italy.
Götz ThomallaUniversitätsklinikum Hamburg-Eppendorf Klinik und Poliklinik für Neurologie Hamburg Germany.
Simon NagelDepartment of Neurology Heidelberg University Hospital Heidelberg Germany.
Else C SandsetDepartment of Neurology Oslo University Hospital Oslo Norway.
Bruce C V CampbellMedicine and Neurology Melbourne Brain Centre at the Royal Melbourne Hospital University of Melbourne Parkville Victoria Australia.
Tudor G JovinCooper Neurological Institute Cooper University Hospital Camden NJ United States.
Raul G NogueiraDepartment of Neurology University of Pittsburgh Medical Center PA.
Jean RaymondNeuroradiologie Interventionelle Centre Hospitalier de l'Universite de Montreal Montreal Canada.
Thanh N NguyenDepartment of Radiology, Neurology Boston Medical Center Boston University School of Medicine Boston MA United States.ORCID https://orcid.org/0000-0002-2810-1685

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The best management of basilar artery occlusion (BAO) remains uncertain. The BASICS (Basilar Artery International Cooperation Study) and the BEST (Basilar Artery Occlusion Endovascular Intervention Versus Standard Medical Treatment) trials reported neutral results. We sought to understand physicians' approaches to BAOs and whether further BAO randomized controlled trials were warranted. Methods: We conducted an online international survey from January to March 2022 to stroke neurologists and neurointerventionalists. Survey questions were designed to examine clinical and imaging parameters under which clinicians would offer (or rescind) a patient with BAO to endovascular therapy (EVT) or best medical management versus enrollment into a randomized clinical trial. Results: Of >3002 invited participants, 1245 responded (41.4% response rate) from 73 countries, including 54.7% stroke neurologists and 43.6% neurointerventionalists. More than 95% of respondents would offer EVT to patients with BAO, albeit in various clinical circumstances. There were 70.0% of respondents who indicated that the BASICS and BEST trials did not change their practice. Only 22.1% of respondents would perform EVT according to anterior circulation occlusion criteria. The selection of patients for BAO EVT by clinical severity, timing, and imaging modality differed according to geography, specialty, and country income level. Over 80% of respondents agreed that further randomized clinical trials for BAO were warranted. Moreover, 45.6% of respondents indicated they would find it acceptable to enroll all trial-eligible patients into the medical arm of a BAO trial, whereas 26.3% would not enroll. Conclusion: Most stroke physicians continue to believe in the efficacy of EVT in selected patients with BAO in spite of BEST and BASICS. There is no consensus on which selection criteria to use, and few clinicians would use anterior circulation occlusion criteria for BAOs. Further randomized clinical trials for BAO are warranted.

Indexed as

basilar artery occlusionendovascular therapyintravenous thrombolysismechanical thrombectomy

Identifiers

PMID41584003
PMCPMC12778823

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.