Evidence map›Paper›PMID 41583915›Full record

ArticleMethodsX2026

Rebuilding life after heart valve surgery: The VALCAR(E)_QoL study on rehabilitation and quality of life.

Piergiuseppe Liuzzi, Camilla Elena Magi, Paolo Iovino, Ercole Vellone, Andrea Mannini, Claudio Macchi, Biagio Nicolosi, Mariachiara Figura, Francesco Limonti, Duccio Frangi and 1 more

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PubMed Full text at PMC Publisher
In one paragraph

Article in MethodsX, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Piergiuseppe LiuzziIRCCS Fondazione Don Carlo Gnocchi ONLUS, Florence, Italy.
Camilla Elena MagiHealth Sciences Department, University of Florence, Florence, Italy.
Paolo IovinoDepartment of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy.
Ercole VelloneDepartment of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy.
Andrea ManniniIRCCS Fondazione Don Carlo Gnocchi ONLUS, Florence, Italy.
Claudio MacchiIRCCS Fondazione Don Carlo Gnocchi ONLUS, Florence, Italy.
Biagio NicolosiHealth Sciences Department, University of Florence, Florence, Italy.
Mariachiara FiguraDepartment of Health Promotion, Maternal and Infant Care, Internal Medicine and Medical Specialties (PROMISE), University of Palermo, Palermo, Italy.
Francesco LimontiDepartment of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy.
Duccio FrangiIRCCS Fondazione Don Carlo Gnocchi ONLUS, Florence, Italy.
Hamilton DollakuIRCCS Fondazione Don Carlo Gnocchi ONLUS, Florence, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The VALCAR(E)_QoL study is a prospective, mixed-methods observational investigation designed to characterize the rehabilitation process and determinants of health-related quality of life in patients undergoing cardiac valve surgery. Conducted at the IRCCS Fondazione Don Carlo Gnocchi in Florence (Italy), the study integrates quantitative and qualitative approaches to capture the multidimensional nature of recovery within the International Classification of Functioning, Disability and Health (ICF) framework. Consecutive patients admitted for inpatient cardiac rehabilitation after valve surgery will be assessed at four time points: pre-surgery (T0), rehabilitation admission (T1), discharge (T2), and six-month follow-up (T3). Data collection includes clinical, functional, and psychosocial indicators, as well as patient-reported outcomes such as the Kansas City Cardiomyopathy Questionnaire (primary outcome), SF-12 Health Survey, and standardized measures of anxiety, depression, stress, self-care, and sleep quality. Qualitative interviews at discharge complement quantitative findings by exploring patients' emotional experiences, perceived barriers, and facilitators of recovery. All data are collected in pseudonymized form through a secure REDCap database and analyzed using multivariate and thematic techniques. This protocol adheres to the STROBE guidelines to ensure methodological transparency and reproducibility. By integrating objective measures and subjective experiences, the VALCAR(E)_QoL study aims to identify clinical and psychosocial predictors of successful rehabilitation and to provide evidence for patient-centered, multidisciplinary models of post-surgical care for individuals recovering from heart valve surgery.

Indexed as

Cardiac rehabilitationFunctional capacityHealth-related quality of lifeInternational Classification of Functioning, Disability and Health (ICF)Patient-reported outcomesPost-surgical recoveryPredictors of rehabilitation outcomesPsychosocial recoverySelf-care and self-efficacy

Identifiers

PMID41583915
PMCPMC12830241

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.