Evidence map›Paper›PMID 41583820›Full record

ArticleArthroscopy, sports medicine, and rehabilitation2025

Osteochondral Autograft Transplantation Coupled With Platelet-Rich Plasma and Hyaluronic Acid Injections Can Yield Favorable Outcomes in Patients With Osteochondral Lesions of the Talus.

George A Rublev, Nivedita Pant, Mohamed Ahmed Mohamed, Tamaz Tamazishvili, Giorgi Khokhashvili, Irakli Gogua, Irakli Kartozia, Giorgi Zimlitski, George Loria, Vazha Gaprindashvili and 2 more

Abstract read
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Article in Arthroscopy, sports medicine, and rehabilitation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

12 authors.

George A RublevFrom Center for Arthrology, Sports Medicine, and Regenerative PRP at MediClub, Tbilisi, Georgia.
Nivedita PantAIETI David Tvildiani Medical University, Tbilisi, Georgia.
Mohamed Ahmed MohamedAIETI David Tvildiani Medical University, Tbilisi, Georgia.
Tamaz TamazishviliFrom Center for Arthrology, Sports Medicine, and Regenerative PRP at MediClub, Tbilisi, Georgia.
Giorgi KhokhashviliFrom Center for Arthrology, Sports Medicine, and Regenerative PRP at MediClub, Tbilisi, Georgia.
Irakli GoguaFrom Center for Arthrology, Sports Medicine, and Regenerative PRP at MediClub, Tbilisi, Georgia.
Irakli KartoziaFrom Center for Arthrology, Sports Medicine, and Regenerative PRP at MediClub, Tbilisi, Georgia.
Giorgi ZimlitskiFrom Center for Arthrology, Sports Medicine, and Regenerative PRP at MediClub, Tbilisi, Georgia.
George LoriaFrom Center for Arthrology, Sports Medicine, and Regenerative PRP at MediClub, Tbilisi, Georgia.
Vazha GaprindashviliFrom Center for Arthrology, Sports Medicine, and Regenerative PRP at MediClub, Tbilisi, Georgia.
Mikheil ZimlitskiFrom Center for Arthrology, Sports Medicine, and Regenerative PRP at MediClub, Tbilisi, Georgia.
Levan NatchkebiaFrom Center for Arthrology, Sports Medicine, and Regenerative PRP at MediClub, Tbilisi, Georgia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To evaluate the outcomes of patients who had osteochondral lesions of the talus treated with osteochondral allograft transplants combined with platelet-rich plasma (PRP) and hyaluronic acid (HA). Methods: We aimed to investigate the outcomes of patients who underwent osteochondral autograft transplantation surgery (OATS) from 2015 to 2022. The inclusion criteria for patients to undergo OATS included a defect size greater than 5 mm and failure of conservative management. The preoperative and postoperative visual analog scale (VAS) and American Orthopaedic Foot & Ankle Society (AOFAS) scores were recorded and subsequently analyzed using a paired Results: At the 12-month follow-up, all 19 patients reported a mean increase in the VAS score of 33.40 (95% confidence interval, 30.9-35.8). The average age was 31 years, and there were 12 male and 7 female patients. Of the 19 patients, 17 reported no restriction of motion, whereas the other 2 patients reported some restriction of dorsiflexion. Ankle function based on the AOFAS scoring system showed good to excellent results in 18 of 19 cases (94%), with no long-term donor-site morbidity and a mean increase of 37.49 (95% confidence interval, 34.7-40). Hardware removal of lag screws was conducted at 12 months after initial surgery; all cases resulted in union of the malleolar osteotomy. The average follow-up time was 3 years. Conclusions: Combining OATS with PRP-HA injections can yield promising results for patients with osteochondral lesions of the talus, showing significant improvement in VAS and AOFAS scores postoperatively. Level of Evidence: Level IV, therapeutic case series.

Identifiers

PMID41583820
PMCPMC12827211

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