ArticleArthroscopy, sports medicine, and rehabilitation2025
Augmenting an Allograft for Anterior Cruciate Ligament Reconstruction With a Collagen Matrix and Bone Marrow Aspirate Concentrate Injection Appears Safe and Produces Favorable Clinical Outcomes at 2-Year Follow-Up.
Article in Arthroscopy, sports medicine, and rehabilitation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Biologic Augmentation in Anterior Cruciate Ligament Reconstruction and Beyond: A Review of PRP and BMAC.Journal of clinical medicine · 2025Review
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: To evaluate clinical outcomes of augmenting an anterior cruciate ligament (ACL) allograft with an amnion matrix wrap and injecting bone marrow aspirate concentrate (BMAC). Methods: We enrolled 10 ACL reconstruction patients aged 22-60 years with hamstring allografts wrapped with an amnion collagen matrix and injected with BMAC in this prospective case series. Participants completed physical therapy and reported outcomes for 2 years. Postoperative magnetic resonance imaging scans were mapped/processed at 3, 6, 9, and 12 months, yielding mean transverse relations time constant (T2∗) and volume values for grafts and bone tunnel integration. Results: We assessed the longitudinal outcomes of allograft augmentation using descriptive statistics and confidence intervals, showing significant increases in average Knee Injury and Osteoarthritis Outcome Score (KOOS Conclusions: This case series demonstrated augmenting hamstring allograft ACL reconstruction with an amnion collagen matrix and injecting BMAC appeared to be safe, and clinical outcomes were favorable up to 2 years postoperation despite having no quantifiable effect on graft maturation. Level of Evidence: Level IV, therapeutic case series.
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Registered trials
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