Evidence map›Paper›PMID 41583797›Full record

ArticleKidney medicine2026

Rituximab-Induced Remission in Proliferative Glomerulonephritis With Monoclonal Immunoglobulin G Deposits: A Case Report With Serial Kidney Biopsies.

Jeong-Hoon Lim, Youn-Sik Oh, Man-Hoon Han, You Hyun Jeon, Hee-Yeon Jung, Ji-Young Choi, Jang-Hee Cho, Sun-Hee Park, Chan-Duck Kim, Yong-Lim Kim and 1 more

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In one paragraph

Article in Kidney medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jeong-Hoon LimDepartment of Internal Medicine, School of Medicine, Kyungpook National University, Kyungpook National University Hospital, Daegu, South Korea.
Youn-Sik OhDepartment of Internal Medicine, School of Medicine, Kyungpook National University, Kyungpook National University Hospital, Daegu, South Korea.
Man-Hoon HanDepartment of Pathology, School of Medicine, Kyungpook National University, Kyungpook National University Hospital, Daegu, South Korea.
You Hyun JeonDepartment of Internal Medicine, School of Medicine, Kyungpook National University, Kyungpook National University Hospital, Daegu, South Korea.
Hee-Yeon JungDepartment of Internal Medicine, School of Medicine, Kyungpook National University, Kyungpook National University Hospital, Daegu, South Korea.
Ji-Young ChoiDepartment of Internal Medicine, School of Medicine, Kyungpook National University, Kyungpook National University Hospital, Daegu, South Korea.
Jang-Hee ChoDepartment of Internal Medicine, School of Medicine, Kyungpook National University, Kyungpook National University Hospital, Daegu, South Korea.
Sun-Hee ParkDepartment of Internal Medicine, School of Medicine, Kyungpook National University, Kyungpook National University Hospital, Daegu, South Korea.
Chan-Duck KimDepartment of Internal Medicine, School of Medicine, Kyungpook National University, Kyungpook National University Hospital, Daegu, South Korea.
Yong-Lim KimDepartment of Internal Medicine, School of Medicine, Kyungpook National University, Kyungpook National University Hospital, Daegu, South Korea.
Yong-Jin KimDepartment of Pathology, School of Medicine, Kyungpook National University, Kyungpook National University Hospital, Daegu, South Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Proliferative glomerulonephritis with monoclonal IgG deposits (PGNMID) is a rare form of monoclonal gammopathy of renal significance (MGRS). The natural history and optimal treatment are poorly defined, particularly when circulating monoclonal proteins or hematologic clones are undetectable. We report a 57-year-old woman with biopsy-confirmed PGNMID who underwent 3 sequential kidney biopsies. The initial biopsy showed a classic membranoproliferative pattern with monotypic IgG-kappa deposits, whereas bone marrow examination showed no clonal plasma cell or B-cell proliferation. Despite corticosteroid-based immunosuppression, proteinuria persisted, and histology worsened on the second biopsy. Rituximab was administered 10 months after diagnosis; a third biopsy 3 months later showed resolution of immune deposits and glomerular proliferation. At 8 months post-rituximab, the patient remained in clinical remission with stable kidney function. This case underscores the value of sequential kidney biopsies to monitor disease activity and treatment response in PGNMID. Rituximab can induce clinical and histologic remission, even when circulating monoclonal proteins are undetectable.

Indexed as

Kidney biopsyproliferative glomerulonephritis with monoclonal IgG depositsrituximabtreatment response

Identifiers

PMID41583797
PMCPMC12830154

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.