Evidence map›Paper›PMID 41583670›Full record

ArticleStroke (Hoboken, N.J.)2023

Validation of the National Institutes of Health Stroke Scale in Intracerebral Hemorrhage.

Wendy Dusenbury, Georgios Tsivgoulis, Jason Chang, Nitin Goyal, Victoria Swatzell, Andrei V Alexandrov, Patrick Lyden, Anne W Alexandrov

Abstract read
In one paragraph

Article in Stroke (Hoboken, N.J.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Early neurological improvement with deferoxamine after intracerebral hemorrhage: A post hoc analysis of the i-DEF trial.International journal of stroke : official journal of the International Stroke Society · 2025
    Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Andexanet alfa: trials just leave us with more questions.Research and practice in thrombosis and haemostasis · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Wendy DusenburyUniversity of Tennessee Health Science Center Memphis TN.ORCID https://orcid.org/0000-0003-4457-4818
Georgios TsivgoulisUniversity of Tennessee Health Science Center Memphis TN.
Jason ChangWashington Hospital Center Washington DC.
Nitin GoyalUniversity of Tennessee Health Science Center Memphis TN.
Victoria SwatzellUniversity of Tennessee Health Science Center Memphis TN.
Andrei V AlexandrovUniversity of Tennessee Health Science Center Memphis TN.
Patrick LydenZilkha Neurogenetic Institute at the Keck School of Medicine of USC Los Angeles CA.
Anne W AlexandrovUniversity of Tennessee Health Science Center Memphis TN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: We sought to determine if the National Institutes of Health Stroke Scale (NIHSS) has a greater discriminative power than Glasgow coma scale (GCS) to identify patients at risk of poor early functional outcomes and large hematoma volumes. Methods: We prospectively collected clinical assessments, imaging, and outcome data in consecutive patients with intracerebral hemorrhage, and determined the ability of GCS and NIHSS to predict poor functional outcome (modified Rankin scale 3-6) and hematoma volume >30 cm Results: We studied 672 patients with intracerebral hemorrhage (mean age 62±14 years; 56% men; median intracerebral hemorrhage score=1, interquartile range (IQR) 0-2; median intracerebral hemorrhage volume 7 cm Conclusion: The NIHSS has a greater discriminative power than GCS to identify patients at risk of poor early functional outcomes and large hematoma volumes.

Indexed as

Glasgow coma scaleintracerebral hemorrhageNIH stroke scale

Identifiers

PMID41583670
PMCPMC12778679

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.