Evidence map›Paper›PMID 41583656›Full record

ArticleRadiology case reports2026

A case of telangiectatic osteosarcoma arising from the frontal bone.

Akihiko Hayakawa, Yukari Wakabayashi, Masanori Ishida, Elly Arizono, Maki Tanigawa, Toshitaka Nagao, Jun Nishida, Kazuhiro Saito

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In one paragraph

Article in Radiology case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Akihiko HayakawaDepartment of Radiology, Tokyo Medical University, 6-7-1 Nishi-shinjuku, Shinjuku-ku, Tokyo 1600023, Japan.
Yukari WakabayashiDepartment of Radiology, Tokyo Medical University, 6-7-1 Nishi-shinjuku, Shinjuku-ku, Tokyo 1600023, Japan.
Masanori IshidaDepartment of Radiology, Tokyo Medical University, 6-7-1 Nishi-shinjuku, Shinjuku-ku, Tokyo 1600023, Japan.
Elly ArizonoDepartment of Radiology, Tokyo Medical University, 6-7-1 Nishi-shinjuku, Shinjuku-ku, Tokyo 1600023, Japan.
Maki TanigawaDepartment of Anatomic Pathology, Tokyo Medical University, 6-7-1 Nishi-shinjuku, Shinjuku-ku, Tokyo 1600023, Japan.
Toshitaka NagaoDepartment of Anatomic Pathology, Tokyo Medical University, 6-7-1 Nishi-shinjuku, Shinjuku-ku, Tokyo 1600023, Japan.
Jun NishidaDepartment of Orthopedic Surgery, Tokyo Medical University, 6-7-1 Nishi-shinjuku, Shinjuku-ku, Tokyo 1600023, Japan.
Kazuhiro SaitoDepartment of Radiology, Tokyo Medical University, 6-7-1 Nishi-shinjuku, Shinjuku-ku, Tokyo 1600023, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Osteosarcoma of the calvarium is extremely rare, specifically of the telangiectatic subtype, which has few reported cases. Herein, we report a case of telangiectatic osteosarcoma occurring in the frontal bone of a 33-year-old man without notable family or medical history. The patient presented with a painless mass in the frontal region, and computed tomography (CT) imaging and magnetic resonance imaging (MRI) revealed a tumor destructively involving the inner and outer tables of the skull. On T1- and T2-weighted magnetic resonance imaging (MRI) images, the tumor exhibited an isointense signal similar to brain parenchyma with multiple hemorrhagic cavities internally. Furthermore, the solid component of the tumor enhanced intensely on enhanced T1-weighted image; moreover, biopsy revealed giant cells. Thus, based on imaging and biopsy findings, a preoperative diagnosis of aneurysmal bone cyst was initially suspected. However, pathological examination of the entire tumor after resection revealed atypical mitosis. Results of immunohistochemical tests revealed no H3G34W mutation, and molecular genetic analyses revealed no USP6 gene rearrangement, leading to a final diagnosis of telangiectatic osteosarcoma.

Indexed as

Aneurysmal bone cystCalvariumFrontal boneTelangiectatic osteosarcoma

Identifiers

PMID41583656
PMCPMC12828488

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.