Evidence map›Paper›PMID 41583450›Full record

ArticleFrontiers in immunology2025

Prostate-specific membrane antigen targeted organic semiconducting polymer nanoparticles for enhanced photothermal therapy of prostate cancer.

Zhongji Jiang, Xun Zhang, Gaohaer Kadeerhan, Jin Zhang, Jiali Jin, Weijing Hu, Wenmin Guo, Hong Guo, Dongwen Wang

Abstract read
In one paragraph

Article in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Zhongji JiangSchool of Medicine, Southern University of Science and Technology, Shenzhen, Guangdong, China.
Xun ZhangDepartment of Materials Science and Engineering, Southern University of Science and Technology, Shenzhen, Guangdong, China.
Gaohaer KadeerhanCentral Laboratory & Shenzhen Key Laboratory of Epigenetics and Precision Medicine for Cancers, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital and Shenzhen Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Shenzhen, Guangdong, China.
Jin ZhangFirst College of Clinical Medicine, Shanxi Medical University, Taiyuan, Shanxi, China.
Jiali JinFirst College of Clinical Medicine, Shanxi Medical University, Taiyuan, Shanxi, China.
Weijing HuFirst College of Clinical Medicine, Shanxi Medical University, Taiyuan, Shanxi, China.
Wenmin GuoFirst College of Clinical Medicine, Shanxi Medical University, Taiyuan, Shanxi, China.
Hong GuoFirst College of Clinical Medicine, Shanxi Medical University, Taiyuan, Shanxi, China.
Dongwen WangDepartment of Urology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital & Shenzhen Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Shenzhen, Guangdong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Photothermal therapy (PTT) in the second near-infrared window (NIR-II, 1000-1700 nm) enables deep-tissue penetration and reduced off-target damage, offering a promising approach for localized cancer ablation. A major challenge, however, lies in achieving efficient and tumor-specific accumulation of photothermal agents. In this study, we developed a prostate-specific membrane antigen (PSMA)-targeted NIR-II photothermal nanoplatform based on an organic semiconducting polymer (OSP

Indexed as

Antigens, SurfaceGlutamate Carboxypeptidase IINanoparticlesPhotothermal TherapyPolymersProstatic NeoplasmsAnimalsCell Line, TumorHumansMaleMiceSemiconductorsAntigens, SurfaceFOLH1 protein, humanGlutamate Carboxypeptidase IIPolymersNIR-IIorganic semiconducting polymerphotothermal therapy (PTT)prostate cancerprostate-specific membrane antigen (PSMA)tumor microenvironment (TME)

Identifiers

PMID41583450
PMCPMC12827499

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.