Evidence map›Paper›PMID 41583400›Full record

ArticleStroke (Hoboken, N.J.)2024

CASSH Registry: Rationale and Study Design.

Mohamad Ezzeldin, Ali Kerro, Ameer E Hassan, Muhammad Shazam Hussain, Suhas V V Tatapudi, Rime Ezzeldin, Faheem G Sheriff, Peter Kan, Chizoba Ezepue, Kaiz S Asif and 10 more

Abstract read
In one paragraph

Article in Stroke (Hoboken, N.J.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Mohamad EzzeldinDepartment of Neuroendovascular Surgery HCA Houston Healthcare Kingwood Kingwood TX.ORCID https://orcid.org/0000-0001-7740-8774
Ali KerroDepartment of Neurology HCA Houston Healthcare Conroe Conroe TX.
Ameer E HassanDepartment of Neurology Valley Baptist Medical Center Brownsville TX.
Muhammad Shazam HussainDepartment of Neurology Cleveland Clinic Cleveland OH.
Suhas V V TatapudiDepartment of Internal Medicine HCA Houston Kingwood/University of Houston College of Medicine Kingwood TX.
Rime EzzeldinMedicine Jordan University of Science and Technology Irbid Jordan.
Faheem G SheriffDepartment of Neurology Texas Tech University Health Sciences Center El Paso TX.
Peter KanDepartment of Neurosurgery University of Texas Medical Branch Galveston TX.
Chizoba EzepueDepartment of Neurology SSM Health Saint Louis University Hospital St. Louis MO.
Kaiz S AsifDepartment of Neurology Ascension Health and University of Illinois Chicago Chicago IL.
Ramesh GrandhiDepartment of Neurosurgery University of Utah Salt Lake City UT.
Ali AlarajDepartment of Neurosurgery University of Illinois Chicago Chicago IL.
Muhammad NiaziDepartment of Neurology WellSpan Health York PA.
Saif BushnaqDepartment of Neurology Texas Tech University Lubbock TX.
Omar TanweerDepartment of Neurosurgery Baylor St. Luke Medical Center Houston TX.
Kaustubh LimayeDepartment of Neurology Neurological Surgery and Radiology Indiana University School of Medicine Indianapolis.
Tunmi AnwojuDepartment of Clinical Sciences HCA Houston Healthcare Kingwood Kingwood TX.
Zuhair AliDepartment of Clinical Sciences HCA Houston Healthcare Kingwood Kingwood TX.
Osama O ZaidatDepartment of Neurology St. Vincent Medical Center Toledo OH.
Farhan SiddiqDepartment of Neurosurgery University Hospital Missouri Columbia MO.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Carotid artery disease, a major cause of strokes, often results from carotid atherosclerotic stenosis. Although carotid endarterectomy has long been the standard treatment, carotid artery stenting (CAS) emerged as an alternative for high-risk surgical patients. Operator experience plays a crucial role in reducing complications, with neurointerventional specialists demonstrating proficiency in CAS. However, they are often underrepresented in CAS studies. The CASSH (Carotid Artery Stenting Outcomes in Comprehensive Stroke Hospitals) registry aims to provide comprehensive insights into CAS outcomes, particularly when performed by neurointerventionalists at comprehensive stroke centers. Methods: The CASSH is a multicenter, prospective, observational study currently enrolling patients with carotid artery stenosis undergoing CAS performed by neurointerventional physicians. All the participating sites will screen and report cases that meet inclusion criteria, on a monthly basis. The decision of whether to use CAS is at the discretion of the interventionalist. Results: We will collect patients' baseline clinical, demographic, and radiographic data. In addition, we plan to collect procedure variables and postoperative clinical and imaging data. Outcomes include the rate of postoperative symptomatic stroke (hemorrhagic/ischemic), access site complications, in-stent thrombosis, and mortality. Conclusion: Current literature underrepresents neurointerventionalists in CAS studies, especially as it pertains to procedural expertise and outcomes. CASSH is a prospective observational study that will enhance our understanding of CAS management and outcomes, emphasizing the benefits of neurointerventional expertise within comprehensive stroke centers.

Indexed as

carotid artery stenosiscarotid artery stentingcomprehensive stroke centerneuro interventional surgeon

Identifiers

PMID41583400
PMCPMC11864738

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.