Evidence map›Paper›PMID 41583297›Full record

ArticleCureus2025

Surgical Treatment of Primary Localized Cutaneous Nodular Amyloidosis of the Nose: Resection and Reconstruction With a Nasolabial Flap.

Daisuke Hirao, Tomoki Himejima, Michika Fukui, Masakatsu Hihara, Natsuko Kakudo

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Daisuke HiraoDepartment of Plastic and Reconstructive Surgery, Kansai Medical University, Hirakata, JPN.
Tomoki HimejimaDepartment of Plastic and Reconstructive Surgery, Yao Municipal Hospital, Yao, JPN.
Michika FukuiDepartment of Plastic and Reconstructive Surgery, Kansai Medical University, Hirakata, JPN.
Masakatsu HiharaDepartment of Plastic and Reconstructive Surgery, Kansai Medical University, Hirakata, JPN.
Natsuko KakudoDepartment of Plastic and Reconstructive Surgery, Kansai Medical University, Hirakata, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primary localized cutaneous nodular amyloidosis (PLCNA) is a rare form of amyloidosis limited to the skin. A 39-year-old woman had noticed a tumor on her right nasal ala for five years. She presented it to our hospital after developing a similar lesion on her right cheek. Histopathological examination following surgical excision revealed AL amyloidosis (κ-light chain type), ruling out systemic amyloidosis and confirming the diagnosis of PLCNA. The nasal lesion was excised and reconstructed with a nasolabial flap, resulting in excellent aesthetic and functional outcomes. No recurrence has been observed during a 21-month follow-up. PLCNA in young adults is rare, and long-term follow-up is crucial due to the potential for systemic progression. This case highlights the importance of accurate diagnosis and the benefits of local flap reconstruction in cosmetically sensitive areas.

Indexed as

amyloidosiscutaneousnasolabial flapnoseplcna

Identifiers

PMID41583297
PMCPMC12823334

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.