Evidence map›Paper›PMID 41583215›Full record

ArticleCureus2025

Observed Reduction in Urinary Toxin Excretion With Extracorporeal Blood Oxygenation and Ozonation (EBOO) Treatment in an 88-Year-Old With Chronic Anemia: A Case Report.

S J Bennett, Jonathann Kuo, Serena Wang, Richard J Salway

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

S J BennettPain Management, Hudson Health, New York, USA.
Jonathann KuoPain Management, Extension Health, Hudson Medical Group, New York, USA.
Serena WangPain Management, Hudson Medical Group, New York, USA.
Richard J SalwayEmergency Medicine, Extension Health, New York, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Extracorporeal blood oxygenation and ozonation (EBOO) is a hemodialysis-adjacent ex vivo filtration system. We present a case of an 88-year-old female with chronic iron-deficiency anemia with high urinary levels of mycotoxins, heavy metals, and other environmental toxins. She underwent two distinct series of three sequential EBOO treatments, with interval monitoring of her urinary toxin/creatinine ratios (µg/g) at baseline, after completion of EBOO series I, and after completion of EBOO series II. The average decline from baseline to completion of EBOO series II was 64.8% for the mycotoxins, 25.7% for the heavy metals, and 55.1% for the environmental toxins. Though there was no control for ongoing exposure, all of her toxin levels ultimately decreased except nickel. Her hemoglobin levels remained largely unchanged over the course of treatment. Thus, EBOO should be considered a potential therapy in patients with environmental toxicities that may be contributing to chronic conditions.

Indexed as

anemiaebooenvironmental toxinsextracorporeal blood oxygenation and ozonationheavy metalsiron-deficiency anemiamycotoxinsozonetoxins

Identifiers

PMID41583215
PMCPMC12826612

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.