ReviewCureus2025
Renal Cell Carcinoma Metastasizing to the Myocardium: A Comprehensive Literature Review of Diagnostic and Therapeutic Challenges.
Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Renal cell carcinoma is a type of cancer that occurs in adults and typically metastasizes to the lungs, liver, bone, and brain. Cardiac involvement is far less common and often goes unrecognized, as its clinical manifestations can mimic those of more prevalent cardiopulmonary conditions, leading to substantial morbidity. This review examines the epidemiology, mechanisms of spread, patterns of presentation, diagnostic approaches, and treatment strategies for renal cell carcinoma involving the myocardium. Mechanisms include direct extension through the inferior vena cava to the right atrium, hematogenous dissemination, and, less frequently, lymphatic spread. Clinical findings range from incidental imaging abnormalities to presentations involving heart failure, arrhythmias, or cardiac tamponade. Diagnosis relies on multimodal imaging, with echocardiography and cardiac MRI providing complementary information. Management options include surgery in selected cases and systemic therapies, although available evidence is mainly derived from case reports and small series. Overall outcomes remain poor. Early recognition, coordinated multidisciplinary care, and further research are needed to guide management in this rare clinical setting.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.