Evidence map›Paper›PMID 41583157›Full record

ArticleCureus2025

Bite to Brain: Unwitnessed Pediatric Neurotoxic Envenomation Mimicking Brain Death.

Pawan K Ghanghoriya, Shaunak Rangarh, Jayas Jagan, Monica Lazarus, Arvinder Wander

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Pawan K GhanghoriyaDepartment of Paediatrics, Netaji Subhash Chandra Bose Medical College, Jabalpur, IND.
Shaunak RangarhDepartment of Paediatrics, Netaji Subhash Chandra Bose Medical College, Jabalpur, IND.
Jayas JaganDepartment of Paediatrics, Netaji Subhash Chandra Bose Medical College, Jabalpur, IND.
Monica LazarusDepartment of Paediatrics, Netaji Subhash Chandra Bose Medical College, Jabalpur, IND.
Arvinder WanderDepartment of Paediatrics, All India Institute of Medical Sciences, Bathinda, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Snakebite envenomation is an important yet treatable cause of mortality. When the bite is witnessed, clinical diagnosis is straightforward, enabling prompt administration of anti-snake venom (ASV). However, in the absence of a witnessed event or local bite-site signs, diagnosing snakebite becomes challenging for emergency physicians. Neurotoxic envenomation, particularly from krait species, can closely mimic acute flaccid paralysis (AFP), often leading to diagnostic uncertainty. We report the case of an adolescent girl who presented with AFP and encephalopathy. A 13-year-old girl from a rural area presented in the early morning during the monsoon season with acute flaccid paralysis, coma, and signs of brainstem dysfunction (dilated and fixed pupils, absent doll's eye, and gag reflex). After excluding alternative diagnoses and identifying subtle bite marks, a probable krait bite was considered. The patient made a complete recovery following timely ASV administration, 22 days of mechanical ventilation, and supportive care. Krait bite should be considered in previously healthy children who present with early morning neuroparalytic syndrome (EMNS) or a brain-death-like clinical picture during the monsoon season.

Indexed as

brain death mimickerearly morning neuroparalytic syndromekrait biteneurotoxic envenomationunwitnessed snake bite

Identifiers

PMID41583157
PMCPMC12828855

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.