Evidence map›Paper›PMID 41583020›Full record

ArticleThe Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale2026

Clinical Characteristics and Cytokines of Children With Lower Respiratory Tract Infection Caused by Influenza A After COVID-19.

Yue Qi, Xinqian Xu, Hongrong Dan, Miao He, Qinxin Zheng, Xing Liu, Li Xiang, Yingshun Zhou, Cheng Li

Abstract read
In one paragraph

Article in The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Clinical Characteristics and Cytokines of Children With Lower Respiratory Tract Infection Caused by Influenza A After COVID-19.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yue QiDepartment of Pediatrics, The Affiliated Hospital, Southwest Medical University, Luzhou, China, swmu.edu.cn.
Xinqian XuDepartment of Pediatrics, The Affiliated Hospital, Southwest Medical University, Luzhou, China, swmu.edu.cn.
Hongrong DanDepartment of Pediatrics, The Affiliated Hospital, Southwest Medical University, Luzhou, China, swmu.edu.cn.
Miao HeDepartment of Pediatrics, The Affiliated Hospital, Southwest Medical University, Luzhou, China, swmu.edu.cn.
Qinxin ZhengDepartment of Pediatrics, The Affiliated Hospital, Southwest Medical University, Luzhou, China, swmu.edu.cn.
Xing LiuDepartment of Cardiology, The Affiliated Hospital, Southwest Medical University, Luzhou, China, swmu.edu.cn.ORCID https://orcid.org/0000-0002-3087-2470
Li XiangDepartment of Pathogen Biology, The Public Platform of the Pathogen Biology Technology, School of Basic Medicine, Southwest Medical University, Luzhou, China, swmu.edu.cn.
Yingshun ZhouDepartment of Pathogen Biology, The Public Platform of the Pathogen Biology Technology, School of Basic Medicine, Southwest Medical University, Luzhou, China, swmu.edu.cn.ORCID https://orcid.org/0000-0003-4978-0098
Cheng LiDepartment of Pediatrics, The Affiliated Hospital, Southwest Medical University, Luzhou, China, swmu.edu.cn.ORCID https://orcid.org/0009-0006-1311-0710

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: To date, there is a lack of research on the clinical characteristics and cytokine profiles in children with influenza A following COVID-19 infection. Methods: Children with influenza A lower respiratory tract infection who were hospitalized in the Department of Pediatrics of the Affiliated Hospital of Southwest Medical University from March 15 to April 15, 2023, were divided into mild and severe groups according to their symptoms, followed up on the COVID-19 infection status by telephone, and selected those who had been infected with COVID-19 for comparison of clinical characteristics and cytokines. Results: An analysis of influenza A case in children with prior SARS-CoV-2 infection revealed that the proportion of previous infection was significantly higher in the severe group compared to the mild group. Univariate analysis indicated significant differences between the two groups in the incidence of convulsions, concurrent or secondary bacterial infections, white blood cell (WBC) count, lymphocyte percentage (L%), neutrophil percentage (N%), and interferon-induced protein-10 (IP-10) (all Conclusion: IP-10 and WBC count serve as diagnostic biomarkers for severe influenza infection following SARS-CoV-2 infection, and their combination significantly enhances diagnostic performance.

Indexed as

childrenclinical characteristicCOVID-19cytokineinfluenza A

Identifiers

PMID41583020
PMCPMC12828273

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.