Evidence map›Paper›PMID 41582976›Full record

ArticleStroke (Hoboken, N.J.)2022

Association of the

Eriko Yamaguchi, Takeshi Yoshimoto, Shiori Ogura, Kozue Saito, Satoshi Saito, Yorito Hattori, Kazuo Wasida, Kunihiro Nishimura, Kazunori Toyoda, Masatoshi Koga and 1 more

Registry-linked trialAbstract read
In one paragraph

Article in Stroke (Hoboken, N.J.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02251665 (National Cerebral and Cardiovascular Center), which is not on this map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02251665 active not recruitingnot on this map

National Cerebral and Cardiovascular Center (NCVC) Stroke Registry

TypeobservationalSponsorNational Cerebral and Cardiovascular Center, JapanRan2016 to 2028Enrolled5,374ConditionsStroke, AcuteArmsNo intervention
3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Genes · 2025
    Review
  5. Article
  6. Relationship BetweenJournal of the American Heart Association · 2025
    Article
  7. Review
  8. Brain communications · 2025
    Article
  9. Detailed phenotype ofStroke and vascular neurology · 2023
    Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Eriko YamaguchiDepartment of Neurology National Cerebral and Cardiovascular Center 6-1, Kishibe-Shimmachi Suita Osaka 5648565 Japan.
Takeshi YoshimotoDepartment of Neurology National Cerebral and Cardiovascular Center 6-1, Kishibe-Shimmachi Suita Osaka 5648565 Japan.
Shiori OguraDepartment of Cerebrovascular Medicine National Cerebral and Cardiovascular Center 6-1, Kishibe-Shimmachi Suita Osaka 5648565 Japan.
Kozue SaitoDepartment of Neurology National Cerebral and Cardiovascular Center 6-1, Kishibe-Shimmachi Suita Osaka 5648565 Japan.
Satoshi SaitoDepartment of Neurology National Cerebral and Cardiovascular Center 6-1, Kishibe-Shimmachi Suita Osaka 5648565 Japan.
Yorito HattoriDepartment of Neurology National Cerebral and Cardiovascular Center 6-1, Kishibe-Shimmachi Suita Osaka 5648565 Japan.
Kazuo WasidaDepartment of Neurology National Cerebral and Cardiovascular Center 6-1, Kishibe-Shimmachi Suita Osaka 5648565 Japan.
Kunihiro NishimuraDepartment of Preventive Medicine and Epidemiologic Informatics National Cerebral and Cardiovascular Center 6-1, Kishibe-Shimmachi Suita Osaka 5648565 Japan.
Kazunori ToyodaDepartment of Cerebrovascular Medicine National Cerebral and Cardiovascular Center 6-1, Kishibe-Shimmachi Suita Osaka 5648565 Japan.
Masatoshi KogaDepartment of Cerebrovascular Medicine National Cerebral and Cardiovascular Center 6-1, Kishibe-Shimmachi Suita Osaka 5648565 Japan.
Masafumi IharaDepartment of Neurology National Cerebral and Cardiovascular Center 6-1, Kishibe-Shimmachi Suita Osaka 5648565 Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: We investigated the impact of the p.R4810K variant of Methods: We examined consecutive Japanese patients with ischemic stroke who underwent carotid ultrasonography between 2015 and 2019. Patient background and the carotid ultrasonography-measured outer diameter of extracranial cervical arteries, including the common carotid artery, internal carotid artery, external carotid artery, and cervical VA, were compared between variant carriers and noncarriers. Outer diameters of each artery were defined as the mean distance from far to near wall adventitia of right and left target arteries using carotid ultrasonography. The average diameter of both cervical portions of common carotid arteries, internal carotid arteries, external carotid arteries, and the dominant side diameter of both cervical VAs were used. Results: Of the 617 adult patients (204 women; median age, 74 years) analyzed, 26 (4.2%) carried the Conclusion: Registration: URL: https://www.clinicaltrials.gov; Unique identifier: NCT02251665.

Indexed as

cervical arteryischemic strokeouter diameterRNF213 variant

Identifiers

PMID41582976
PMCPMC12778827

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.