ArticleStroke (Hoboken, N.J.)2022
Importance of First Pass Reperfusion in Endovascular Stroke Care - Insights From Thrombectomy and Aneurysm Registry (STAR).
Article in Stroke (Hoboken, N.J.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed.
- Enhanced Complete Clot Ingestion with the ALGO Smart Pump: Preclinical Evidence Supporting Aspiration Efficiency in Mechanical Thrombectomy.Clinical neuroradiology · 2026Article
- Improved technical outcomes with converting thrombectomy techniques after failed first pass recanalization.Journal of neurointerventional surgery · 2025Article
- Impact of the Recanalization Level and the First-Pass Effect on Functional Outcomes in Patients After M2 MCA Occlusion Thrombectomy.Journal of clinical medicine · 2025Article
- Endovascular Thrombectomy for Acute Ischemic Stroke due to Calcified Cerebral Emboli.Stroke research and treatment · 2025Article
- First pass effect as an independent predictor of functional outcomes in medium vessel occlusions: An analysis of an international multicenter study.European stroke journal · 2024Article
Corrections and comments
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Authors and funding
37 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Mechanical thrombectomy has become the first-line treatment strategy for patients with large-vessel occlusion strokes. Often >1 thrombectomy maneuver is necessary to achieve reperfusion. A first-pass (FP) effect with improved functional outcomes after mechanical thrombectomy has been described. Aim of the present study is to investigate the FP effect in a large, international, multicenter stroke database. Methods: Patients who underwent mechanical thrombectomy for large-vessel occlusion stroke in the anterior cerebral circulation between January 2014 and January 2021 and achieved complete reperfusion were identified from the STAR (Stroke Thrombectomy and Aneurysm Registry). We compared functional outcomes of patients with FP (defined as modified treatment in cerebral ischemia score 3 after a single thrombectomy maneuver) versus multiple-pass complete reperfusion (defined as modified treatment in cerebral ischemia 3 after ≥1 thrombectomy maneuver). Results: A total of 1481 patients with anterior circulation large-vessel occlusion stroke and successful recanalization were included in the analysis. FP complete recanalization was achieved in 778 patients versus 703 patients with multiple-pass complete reperfusion. Patients with FP complete recanalization had higher Alberta Stroke Programme Early CT [Computed Tomography] Score at baseline (9 [7-10] versus 8 [7-10]; Conclusions: This analysis of a large, multicenter stroke database confirms the importance of FP reperfusion in endovascular stroke care.
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