Evidence map›Paper›PMID 41582966›Full record

ArticleStroke (Hoboken, N.J.)2022

INFluence of Revascularization Attempts on Clinical Outcomes of Mechanical Thrombectomy Patients and its Economic BURDEN.

Jack Alderson, Darragh Herlihy, Aidan Hegarty, Paul Brennan, Sarah Power, Alan O'Hare, Matthew Crockett, Cindy Tong, Thibaut Galvain, Mesut Kocaman and 2 more

Abstract read
In one paragraph

Article in Stroke (Hoboken, N.J.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Endovascular Detection of Catheter-Thrombus Contact by Vacuum Excitation.IEEE transactions on bio-medical engineering · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Jack AldersonDepartment of Neuroradiology Beaumont Hospital Dublin Ireland.ORCID https://orcid.org/0000-0003-1275-5737
Darragh HerlihyDepartment of Neuroradiology Beaumont Hospital Dublin Ireland.
Aidan HegartyDepartment of Neuroradiology Beaumont Hospital Dublin Ireland.
Paul BrennanDepartment of Neuroradiology Beaumont Hospital Dublin Ireland.
Sarah PowerDepartment of Neuroradiology Beaumont Hospital Dublin Ireland.
Alan O'HareDepartment of Neuroradiology Beaumont Hospital Dublin Ireland.
Matthew CrockettDepartment of Neuroradiology Beaumont Hospital Dublin Ireland.
Cindy TongJohnson and Johnson Medical Devices NJ.
Thibaut GalvainJohnson and Johnson Medical SAS Issy les Moulineaux France.
Mesut KocamanJohnson and Johnson Medical SAS Issy les Moulineaux France.
Alexandra EhmJohnson & Johnson Medical GmbH Norderstedt Germany.
John ThorntonDepartment of Neuroradiology Beaumont Hospital Dublin Ireland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Emerging evidence suggests that clinical and economic benefits of treatment with mechanical thrombectomy vary by level of reperfusion achieved, and the number of passes required to achieve revascularization. This study aimed to investigate the Methods: Primary clinical outcomes were reperfusion (modified thrombolysis in cerebral infarction 2b-3 or <2b) and functional outcome (90-day modified Rankin Scale ≤2 or modified Rankin Scale >2) among patients treated with 1-3 passes compared with ≥4 passes. Multivariable generalized linear models examined the association between number of passes with outcomes, with adjustment for covariates that may affect outcomes (eg, age, pre-procedure modified Rankin Scale, National Institutes of Health Stroke Scale, Alberta Stroke Program Early CT Score, occlusion site, time from symptom onset to groin puncture). A 90-day decision-tree and Markov model with a 5-year time horizon evaluated the cost-effectiveness of mechanical thrombectomy from the Irish public healthcare payer perspective. Results: Eight hundred twenty three patients met the inclusion criteria. Compared with patients in the ≥4 passes group, patients in the 1-3 passes group achieved a significantly higher rate of successful reperfusion (94% versus 78%, odds ratio [OR], 4.7; Conclusion: This study illustrates that the number of passes has a significant effect on both clinical outcomes and health care costs.

Indexed as

costfirst passstrokethrombectomy

Identifiers

PMID41582966
PMCPMC12778836

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.