Evidence map›Paper›PMID 41582964›Full record

ArticleStroke (Hoboken, N.J.)2022

Brain Aneurysm Biology: What Can We Learn From Imaging?

Edgar A Samaniego

Abstract readEditorial
In one paragraph

Article in Stroke (Hoboken, N.J.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Cerebral Aneurysm: Filling the Gap Between Pathophysiology and Nanocarriers.International journal of molecular sciences · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Edgar A SamaniegoUniversity of Iowa Iowa City IA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aneurysmal subarachnoid hemorrhage portends a high risk of mortality and disability. The clinical and radiological assessment of the risk of a brain aneurysm rupture would aid clinicians in triaging patients for treatment versus observation. However, the specific mechanism underlying the formation, growth, and rupture of brain aneurysms is not known. The development of high-resolution magnetic resonance imaging and the refinement of postacquisition processing protocols have made it possible to analyze the aneurysm wall in detail. The 7T and 3T magnetic resonance imaging scanners provide high spatial resolution images with a high signal-to-noise ratio. The structure, morphology, location, and enhancement features of the aneurysm wall can be characterized with this level of detailed images. Abnormal wall characteristics can then be correlated with blood flow parameters, presence of inflammation, and pathological conditions of the wall. These imaging and analysis tools provide a unique opportunity to estimate the risk of aneurysm development and growth and to better identify novel markers of intracranial aneurysm instability. Morphological analysis of individual aneurysms combined with detailed characterization of the aneurysm wall, and clinical patient information could lead to an accurate and personalized risk prediction of aneurysm rupture.

Identifiers

PMID41582964
PMCPMC12778862

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.