ArticleHuman vaccines & immunotherapeutics2026
Gender-neutral prevention: HPV vaccination willingness and related cancer awareness among Chinese parents of boys and girls.
Article in Human vaccines & immunotherapeutics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Following the approval of human papillomavirus (HPV) vaccination for males in China in January 2025, this study aimed to investigate parental knowledge of HPV, willingness to recommend HPV vaccination for their children, and associated determinants. The study also assessed parental awareness of HPV-associated oropharyngeal cancer (OPC) among parents of minor boys and girls in China. A cross-sectional online survey of parents in Shandong Province conducted from February to March 2025 yielded 1251 submissions, with 1041 valid questionnaires retained after applying prespecified exclusion criteria (refer to flowchart). Data were collected using anonymous self-administered questionnaires that covered demographic characteristics, knowledge of HPV, attitudes toward vaccination, vaccination intentions, and perceived barriers. Among the 1041 parents who completed the survey, 71.3% were aware of HPV and the vaccination program for girls, while only 35.73% were aware of the newly approved program for boys. After receiving information about the vaccine, 62% expressed an intention to vaccinate their child, 10% declined, and 28% remained undecided. Parents of daughters demonstrated significantly higher vaccination intent compared to parents of sons (OR = 0.110, 95% CI: 0.077-0.157,
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