Evidence map›Paper›PMID 41582157›Full record

ArticleBMC oral health2026

Efficacy of piezoelectric surgery in the conservative management of unicystic ameloblastoma: a 5-year retrospective cohort study.

Alessandro Antonelli, Selene Barone, Elena Calabria, Vincenzo Greco, Antonio Madonna, Francesco Bennardo, Giulia Brunello, Amerigo Giudice

Abstract read
In one paragraph

Article in BMC oral health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Alessandro Antonelli *School of Dentistry, Department of Health Science, Magna Graecia University of Catanzaro, Viale Europa, 88100, Catanzaro, Italy.
Selene Barone *School of Dentistry, Department of Health Science, Magna Graecia University of Catanzaro, Viale Europa, 88100, Catanzaro, Italy.
Elena CalabriaSchool of Dentistry, Department of Health Science, Magna Graecia University of Catanzaro, Viale Europa, 88100, Catanzaro, Italy.
Vincenzo GrecoSchool of Dentistry, Department of Health Science, Magna Graecia University of Catanzaro, Viale Europa, 88100, Catanzaro, Italy.
Antonio MadonnaSchool of Dentistry, Department of Health Science, Magna Graecia University of Catanzaro, Viale Europa, 88100, Catanzaro, Italy.
Francesco BennardoSchool of Dentistry, Department of Health Science, Magna Graecia University of Catanzaro, Viale Europa, 88100, Catanzaro, Italy. francesco.bennardo@unicz.it.
Giulia BrunelloDepartment of Oral Surgery, University Hospital of Düsseldorf, Düsseldorf, Germany.
Amerigo GiudiceSchool of Dentistry, Department of Health Science, Magna Graecia University of Catanzaro, Viale Europa, 88100, Catanzaro, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundUnicystic ameloblastoma (UAM) is a subtype of ameloblastoma characterized by less aggressive clinical behavior than its conventional counterpart. Surgical enucleation represents a conservative approach compared to more invasive treatment options; however, the risk of recurrence may be significant. The aim of this study was to evaluate the efficacy of the conservative treatment of UAM associated to a piezoelectric debridement. The main outcome was to evaluate the recurrence rate of UAM over a 5-year follow-up period.

methodsA retrospective cohort study was conducted on patients diagnosed with UAM who underwent enucleation and residual cavity debridement with a piezoelectric surgery device. Clinical and radiological follow-ups were conducted at 6-month intervals over a 5-year period.

resultsTwelve patients (7 female and 5 men) met the inclusion criteria and completed the 5-year follow-up. Lesions predominantly affected the mandible (10 cases), with the posterior region being the most common site. Recurrence occurred in 2 out of 12 patients and was limited to the mural variant of UAM. Both recurrent cases occurred in the posterior mandible and involved the largest lesion sizes observed in this study.

conclusionsThe conservative approach of UAM combining enucleation and piezoelectric bone debridement provided a minimally invasive and effective solution for the management of this pathology, representing a viable alternative to surgical resection.

Indexed as

AmeloblastomaConservative TreatmentJaw NeoplasmsPiezosurgeryAdolescentAdultFemaleFollow-Up StudiesHumansMaleMiddle AgedNeoplasm Recurrence, LocalRetrospective StudiesTreatment OutcomeYoung AdultAmeloblastomaConservative treatmentOdontogenic tumorsPiezosurgeryRecurrence

Identifiers

PMID41582157
PMCPMC12918527

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.