Evidence map›Paper›PMID 41582010›Full record

ArticleRenal failure2026

Protective effects of adenosine triphosphate, thiamin, thiamin pyrophosphate, and their combination against linezolid-induced renal injury and lactic acidosis in rats.

Ozlem Admis, Bulent Yavuzer, Renad Mammadov, Bahadir Suleyman, Durdu Altuner, Ali Sefa Mendil, Nurinisa Yucel, Halis Suleyman

Abstract read
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In one paragraph

Article in Renal failure, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ozlem AdmisDepartment of Medical Biochemistry, Mengucek Gazi Education and Research Hospital, Erzincan Binali Yıldırım University, Erzincan, Turkey.
Bulent YavuzerDepartment of Pharmacology, Faculty of Medicine, Erzincan Binali Yıldırım University, Erzincan, Turkey.
Renad MammadovDepartment of Pharmacology, Faculty of Medicine, Erzincan Binali Yıldırım University, Erzincan, Turkey.
Bahadir SuleymanDepartment of Pharmacology, Faculty of Medicine, Erzincan Binali Yıldırım University, Erzincan, Turkey.
Durdu AltunerDepartment of Pharmacology, Faculty of Medicine, Erzincan Binali Yıldırım University, Erzincan, Turkey.
Ali Sefa MendilDepartment of Pathology, Faculty of Veterinary Medicine, Erciyes University, Kayseri, Turkey.
Nurinisa YucelPharmacy Services Program, Vocational School of Health Services, Erzincan Binali Yıldırım University, Erzincan, Turkey.
Halis SuleymanDepartment of Pharmacology, Faculty of Medicine, Erzincan Binali Yıldırım University, Erzincan, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Linezolid, an oxazolidinone antibiotic effective against Gram-positive pathogens, may cause nephrotoxicity and lactic acidosis during prolonged therapy. This experimental study investigated the protective effects of adenosine triphosphate (ATP), thiamin, thiamin pyrophosphate (TPP), and their combination (ATTP) on linezolid-induced renal injury and lactic acidosis in rats. Thirty-six male Wistar rats were randomly divided into six groups (

Indexed as

Acidosis, LacticAcute Kidney InjuryAdenosine TriphosphateLinezolidThiamineThiamine PyrophosphateAnimalsAnti-Bacterial AgentsAntioxidantsDisease Models, AnimalDrug Therapy, CombinationKidneyMaleOxidative StressRatsRats, WistarAdenosine TriphosphateAnti-Bacterial AgentsAntioxidantsLinezolidThiamineThiamine PyrophosphateAdenosine triphosphate (ATP)linezolidoxidative stressrenal toxicitythiaminthiamin pyrophosphate (TPP)

Identifiers

PMID41582010
PMCPMC12833895

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.