Evidence map›Paper›PMID 41581952›Full record

ReviewGastroenterology clinics of North America2026

Emerging Tissue and Blood Biomarkers for Eosinophilic Esophagitis.

Michelle Russin, Evan S Dellon

Abstract readReview
In one paragraph

Review in Gastroenterology clinics of North America, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Michelle RussinDivision of Gastroenterology and Hepatology, Center for Esophageal Diseases and Swallowing, University of North Carolina School of Medicine, 130 Mason Farm Road, CB# 7080 Bioinformatics Building, Chapel Hill, NC 27599, USA.
Evan S DellonDivision of Gastroenterology and Hepatology, Center for Esophageal Diseases and Swallowing, University of North Carolina School of Medicine, 130 Mason Farm Road, CB# 7080 Bioinformatics Building, Chapel Hill, NC 27599, USA. Electronic address: evan_dellon@med.unc.edu.

Funding

DIGESTIVE DISEASES EPIDEMIOLOGY TRAINING PROGRAMT32DK007634 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ROBERT S. SANDLER · 1990 to 2026
$7.4M
NIDDK NIH HHS T32 DK007634
6 · The paper itself

Abstract

Eosinophilic esophagitis is a chronic, immune-mediated condition traditionally diagnosed and monitored through sedated endoscopy with biopsy. This invasive method, while essential, poses challenges for routine care. This article summarizes current research on noninvasive and minimally invasive biomarkers spanning blood, tissue, and esophageal sampling methods that aim to improve diagnostic accuracy, monitor disease activity, and guide personalized treatment. While no biomarker is yet validated for clinical use, advances in translational science and technology hold promise for integrating these tools into future care models.

Indexed as

BiomarkersEosinophilic EsophagitisEsophagusHumansBiomarkersBiomarkersDiagnosisEoEEosinophilic esophagitisNoninvasivePrediction

Identifiers

PMID41581952
PMCPMC12841845

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.