Evidence map›Paper›PMID 41581509›Full record

ReviewArquivos de neuro-psiquiatria2025

The cognitive cerebellum: a hub for motor, emotional, and executive control.

Renata Barreto Tenório, Andressa Aline Vieira, Gustavo L Franklin, Marcus Vinícius Della Coletta, Hélio Afonso Ghizoni Teive, Carlos Henrique Ferreira Camargo

Abstract readReview
In one paragraph

Review in Arquivos de neuro-psiquiatria, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Renata Barreto TenórioUniversidade Federal do Paraná, Programa de Pós-Graduação em Medicina Interna, Disciplina de Doenças Neurodegenerativas, Curitiba PR, Brazil.ORCID 0000-0002-4802-9430
Andressa Aline VieiraUniversidade Federal do Paraná, Programa de Pós-Graduação em Medicina Interna, Disciplina de Doenças Neurodegenerativas, Curitiba PR, Brazil.ORCID 0009-0001-2821-0021
Gustavo L FranklinUniversidade Federal do Paraná, Setor de Ciências da Saúde, Departamento de Clínica Médica, Serviço de Clínica Médica, Curitiba PR, Brazil.ORCID 0000-0002-0207-3671
Marcus Vinícius Della ColettaUniversidade Federal do Paraná, Programa de Pós-Graduação em Medicina Interna, Disciplina de Doenças Neurodegenerativas, Curitiba PR, Brazil.ORCID 0000-0002-3368-8492
Hélio Afonso Ghizoni TeiveUniversidade Federal do Paraná, Programa de Pós-Graduação em Medicina Interna, Disciplina de Doenças Neurodegenerativas, Curitiba PR, Brazil.ORCID 0000-0003-2305-1073
Carlos Henrique Ferreira CamargoUniversidade Federal do Paraná, Programa de Pós-Graduação em Medicina Interna, Disciplina de Doenças Neurodegenerativas, Curitiba PR, Brazil.ORCID 0000-0002-3533-0347

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

For many decades, the cerebellum was regarded almost exclusively as a structure devoted to motor regulation, responsible for balance, coordination, and the fine-tuning of movement. This view began to change in the 1990s, when studies with patients with isolated cerebellar lesions revealed cognitive and affective disturbances that could not be solely explained by cortical dysfunction. Subsequent anatomical, neuroimaging, and clinical investigations demonstrated robust reciprocal connectivity between the cerebellum and prefrontal regions, while functional imaging confirmed cerebellar activation during cognitive tasks without any motor component. Cognitive impairment linked to cerebellar dysfunction is now recognized as a prominent feature of spinocerebellar ataxias, and it has also been reported in other major neurodegenerative disorders, including Huntington's disease, Parkinson's disease, and Alzheimer's disease. Therefore, the aim of the current narrative review is to synthesize and critically analyze the pathophysiological, neuropathological, genetic, clinical, and neuroimaging evidence that underscores the cerebellum's essential contributions to cognition.

Indexed as

CerebellumCognitionEmotionsExecutive FunctionCerebellar DiseasesCognition DisordersHumansNeurodegenerative Diseases

Identifiers

PMID41581509
PMCPMC12832161

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.