Evidence map›Paper›PMID 41581076›Full record

ArticlePrenatal diagnosis2026

The "Dynamic Tongue Contraction Technique" for Diagnosis of Soft Palate Cleft in Cases of Cleft Lip and Palate Sequence.

Ettie Piura, Yoav Alpert, Or Touval, Offra Engel, Biader Samih Bilal, Yaniv Ebner, Ofer Markovitch

Abstract read
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Article in Prenatal diagnosis, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Ettie PiuraDepartment of Obstetrics and Gynecology, Meir Medical Center, Kefar Sava, Israel.ORCID 0000-0002-6653-9522
Yoav AlpertDepartment of Obstetrics and Gynecology, Meir Medical Center, Kefar Sava, Israel.
Or TouvalDepartment of Obstetrics and Gynecology, Meir Medical Center, Kefar Sava, Israel.ORCID 0000-0002-6933-942X
Offra EngelDepartment of Obstetrics and Gynecology, Meir Medical Center, Kefar Sava, Israel.ORCID 0000-0001-9481-0773
Biader Samih BilalFaculty of Medicine, Tel Aviv University, Tel Aviv-Yafo, Israel.
Yaniv EbnerFaculty of Medicine, Tel Aviv University, Tel Aviv-Yafo, Israel.
Ofer MarkovitchDepartment of Obstetrics and Gynecology, Meir Medical Center, Kefar Sava, Israel.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo present and evaluate the dynamic tongue contraction technique as a novel prenatal sonographic method for detecting soft palate clefts in fetuses with a cleft lip and palate (CLP) sequence.

methodsThis prospective cross-sectional study was conducted at a tertiary care center between September 2023 and September 2024. Seven fetuses with prenatally diagnosed CLP (16-27 weeks' gestation) and 28 control fetuses (14-32 weeks' gestation) underwent 2D ultrasound scans. Three experienced sonographers assessed soft palate integrity using a novel axial-oblique view at the tongue base during fetal tongue contraction.

resultsIn all seven CLP cases involving the soft palate, a central gap became visible during tongue contraction, enabling accurate diagnosis. All control fetuses were confirmed to have an intact palate during both rest and dynamic assessment. Postnatal or post-termination confirmation was available for all CLP cases.

conclusionThe dynamic tongue contraction technique offers a reliable and feasible method for evaluating soft palate integrity in fetuses with cleft lip (CL). This functional assessment improves diagnostic accuracy for secondary palate involvement and may complement or enhance current prenatal imaging strategies.

Indexed as

Cleft LipCleft PalatePalate, SoftTongueUltrasonography, PrenatalAdultCross-Sectional StudiesFemaleHumansPregnancyProspective Studiescleft lipcleft palatecleft soft palateprenatal ultrasound

Identifiers

PMID41581076
PMCPMC12978517

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