Evidence map›Paper›PMID 41580824›Full record

ArticleArchives of public health = Archives belges de sante publique2026

A contemporary overview of emergency myocardial infarction hospitalizations with primary percutaneous coronary intervention in Brazil: regional trends of costs and outcomes.

Sophia A Arzumanov, Andrea D Stephanus, Joaquim Barreto, Luiz Sergio F Carvalho, Andrei C Sposito, Alessandra M Campos-Staffico

Abstract read
In one paragraph

Article in Archives of public health = Archives belges de sante publique, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Regional inequities in myocardial infarction burden in Brazil's public healthcare system.Archives of public health = Archives belges de sante publique · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sophia A ArzumanovDepartment of Pharmacy Sciences, School of Pharmacy and Health Professions, Creighton University, 2500 California Plaza, Omaha, NE, 68178, USA.
Andrea D StephanusLaboratory of Data for Quality of Care and Outcomes Research (LaDa:QCOR), Universidade Católica de Brasília, QS 07, Lote 01, Taguatinga Sul, Brasília, DF, 71966-700, Brazil.
Joaquim BarretoCardiology Division, College of Medical Sciences, Universidade Estadual de Campinas, Rua Tessália Vieira de Camargo, 126, Cidade Universitária Zeferino Vaz, Campinas, SP, 13083-887, Brazil.
Luiz Sergio F CarvalhoLaboratory of Data for Quality of Care and Outcomes Research (LaDa:QCOR), Universidade Católica de Brasília, QS 07, Lote 01, Taguatinga Sul, Brasília, DF, 71966-700, Brazil.
Andrei C SpositoCardiology Division, College of Medical Sciences, Universidade Estadual de Campinas, Rua Tessália Vieira de Camargo, 126, Cidade Universitária Zeferino Vaz, Campinas, SP, 13083-887, Brazil.
Alessandra M Campos-StafficoDepartment of Pharmacy Sciences, School of Pharmacy and Health Professions, Creighton University, 2500 California Plaza, Omaha, NE, 68178, USA. alessandrastaffico@creighton.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPrimary percutaneous coronary intervention (pPCI) is the gold standard treatment for acute myocardial infarction (MI). Yet, its implementation across Brazil's diverse regions remains poorly characterized. Although Brazil's public healthcare system (Sistema Único de Saúde [SUS]) serves approximately 72% of Brazil's population, comprehensive analysis of pPCI utilization patterns and outcomes has been limited. This study aimed to evaluate contemporary trends in pPCI utilization, associated costs, and clinical outcomes across Brazil's regions from 2008 to 2023.

methodsWe conducted a retrospective observational study of emergency MI hospitalizations treated with pPCI using Brazil's Unified Health System databases. Population‑adjusted rates of pPCI, inflation‑adjusted standardized costs, in‑hospital mortality, and densities of registered pPCI‑capable facilities were estimated for Brazil and its five regions. Five‑year interval means and cumulative changes were computed. Statistical significance was evaluated with Z‑tests and 95% confidence intervals.

resultsNational pPCI hospitalizations increased by 190.94%, with marked regional variation. The South reached 26.22 procedures per 100,000 population in 2023, while the North remained critically low (1.49 per 100,000). After inflation adjustment, standardized costs declined nationally (-36.34% per day; -47.12% per hospitalization), yet population‑adjusted in‑hospital mortality rose by 121.74% over the study period. Across regions, most pPCI‑capable facilities were private rather than public or philanthropic. Disparities were most pronounced between the South and North regions, reflecting broader socioeconomic inequities.

conclusionBrazil has substantially increased pPCI utilization, but persistent regional disparities and rising population‑adjusted mortality highlight systemic challenges in timely, high‑quality care. Targeted interventions - standardized protocols, strengthened infrastructure and transfer networks in underserved areas, and focused investment - are needed to improve equity and cardiovascular outcomes nationwide.

Indexed as

Health care costsHealth disparitiesMortalityMyocardial infarctionPrimary percutaneous coronary interventionRegional health planningUnified health system (SUS)

Identifiers

PMID41580824
PMCPMC12914957

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.