Evidence map›Paper›PMID 41580684›Full record

ArticleBMC neurology2026

Polycythemia vera and stiff-person syndrome: a case report.

Haixia Mu, Fengxia Ji, Rongfeng Du, Lingyan Hou, Yanni Li, Xiujun Yang, Chunxiao Shao, Kaijuan Hou, Yanping Wang

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC neurology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Haixia MuDepartment of Hematology, Laizhou People's Hospital, No. 1718 Wuli Street, Yantai, Shandong, 261400, China.
Fengxia JiDepartment of Hematology, Laizhou People's Hospital, No. 1718 Wuli Street, Yantai, Shandong, 261400, China.
Rongfeng DuDepartment of Hematology, Laizhou People's Hospital, No. 1718 Wuli Street, Yantai, Shandong, 261400, China.
Lingyan HouDepartment of Hematology, Laizhou People's Hospital, No. 1718 Wuli Street, Yantai, Shandong, 261400, China.
Yanni LiDepartment of Hematology, Laizhou People's Hospital, No. 1718 Wuli Street, Yantai, Shandong, 261400, China.
Xiujun YangDepartment of Hematology, Laizhou People's Hospital, No. 1718 Wuli Street, Yantai, Shandong, 261400, China.
Chunxiao ShaoDepartment of Hematology, Laizhou People's Hospital, No. 1718 Wuli Street, Yantai, Shandong, 261400, China.
Kaijuan HouDepartment of Hematology, Laizhou People's Hospital, No. 1718 Wuli Street, Yantai, Shandong, 261400, China.
Yanping WangDepartment of Hematology, Laizhou People's Hospital, No. 1718 Wuli Street, Yantai, Shandong, 261400, China. wangyanpingchina@yeah.net.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPolycythemia vera (PV) is a myeloproliferative neoplasm, characterized by trilineage hypercellularity, which increases the risk of thrombosis. Stiff-person syndrome (SPS) is a very rare autoimmune neuronal excitability disorder, in which antibodies disrupt the balance between excitatory and inhibitory neurotransmitters, leading to stiffness and spasms of agonist and antagonist muscles. CASE PRESENTATION: This report describes the first known case of PV and SPS occurring simultaneously in a middle-aged male patient. He presented with back stiffness and painful abdominal spasms and was found to have erythrocytosis incidentally. He had high JAK2 V617F mutation burden and was positive for anti-GAD65 antibody. Progressively intensified therapy was given until his symptoms resolved.

conclusionsThis case highlights the diagnostic and therapeutic challenges of these conditions as well as the need for further exploration of potential shared molecular mechanisms between PV and SPS.

Indexed as

Polycythemia VeraStiff-Person SyndromeHumansJanus Kinase 2MaleMiddle AgedJanus Kinase 2anti-GAD antibodiesAutoimmune neurological diseasesJanus kinase 2Myeloproliferative neoplasms

Identifiers

PMID41580684
PMCPMC12915012

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