Evidence map›Paper›PMID 41580649›Full record

ArticleBMC medical education2026

Peer-assisted learning combined with problem-based learning enhances clinical reasoning and knowledge application among medical students.

Jingtao Xie, Ziyan Chen, Duhuang Lin, Guansheng Zhuang, Ziyuan Zheng, Yun Su, Gang Xin

Abstract read
In one paragraph

Article in BMC medical education, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jingtao XieDepartment of Microbiology and Immunology, Shantou University Medical College, Shantou, 515041, China.
Ziyan ChenDepartment of Microbiology and Immunology, Shantou University Medical College, Shantou, 515041, China.
Duhuang LinDepartment of Microbiology and Immunology, Shantou University Medical College, Shantou, 515041, China.
Guansheng ZhuangDepartment of Microbiology and Immunology, Shantou University Medical College, Shantou, 515041, China.
Ziyuan ZhengDepartment of Microbiology and Immunology, Shantou University Medical College, Shantou, 515041, China.
Yun SuDepartment of Microbiology and Immunology, Shantou University Medical College, Shantou, 515041, China. g_ysu@stu.edu.cn.ORCID http://orcid.org/0000-0002-1408-8459
Gang XinDepartment of Microbiology and Immunology, Shantou University Medical College, Shantou, 515041, China. gxin@stu.edu.cn.ORCID http://orcid.org/0000-0002-3669-3959

Funding

Guangdong Higher Education Teaching Reform Project 2023-662Teaching Research and Reform Projects of Shantou University Medical College 2024-01Undergraduate Innovation and Entrepreneurship Training Program of Shantou University Medical College 2024-68
6 · The paper itself

Abstract

backgroundProblem-based learning (PBL) and peer-assisted learning (PAL) have been progressively incorporated into medical education to promote active learning methodologies. Nevertheless, PBL implementation is frequently hampered by practical challenges, such as excessive faculty workload that consumes limited resources, while PAL efficacy can be constrained by ambiguities in learning objectives and the proficiency of peer tutors. This study trialed a model integrating PAL and PBL-Peer-Assisted Problem-Based Learning (PA-PBL)-problem-based learning facilitated by peer tutors, and evaluated PA-PBL for enhancing clinical reasoning and the application of knowledge among medical students.

methodsA non-randomized controlled trial was conducted. A total of 523 undergraduates taking the mandatory module "Infection and Immunity" for second-year clinical medicine major students in Shantou University Medical College were enrolled in this study, of which 134 were in the experimental group, and PA-PBL was used to supplement lecture-based learning; 389 students were designed as the control group, receiving the lecture-based learning. Learning outcomes were assessed through quizzes, final examinations and student surveys, structured according to the Kirkpatrick model to evaluate reaction and learning levels. Non-parametric test, χ

resultsThe quiz scores of the experimental group were increased by 12.3%, 12.8%, 9.8% and 6.8% respectively (P < 0.05). The scores of knowledge-recall MCQs, case-based MCQs, and MEQs in the experimental group were all higher than those in the control group, and the difference was statistically significant (P < 0.05). Following four rounds of study, students in the experimental group achieved a higher academic ranking than after two rounds (P < 0.05). The results of the questionnaire showed that the average scores of the experimental group on reaction and learning level of Kirkpatrick model were higher than 4.7 points (5-point Likert Scale).

conclusionsPA-PBL is shown to improve knowledge mastery, enhance skills in case analysis, and cultivate clinical reasoning and knowledge application abilities. Moreover, it may reduce educational expenditures, indicating that PA-PBL is a valuable methodology deserving broader implementation.

Indexed as

Clinical CompetenceClinical ReasoningEducation, Medical, UndergraduatePeer GroupProblem-Based LearningStudents, MedicalEducational MeasurementFemaleHumansMaleYoung AdultClinical reasoningKirkpatrick modelMedical educationPeer-assisted learningProblem-based learning

Identifiers

PMID41580649
PMCPMC12911268

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.