Evidence map›Paper›PMID 41579267›Full record

ReviewVeterinary research communications2026

A critical review of American Trypanosomiasis (AT) in dogs with the current distribution of cases in Brazil and a diagnostic approach for veterinary clinicians.

José Atanásio de Oliveira Neto, Geovana Mergulhão da Silva, Samuel Souza Silva, Tatiene Rossana Móta Silva, Gílcia Aparecida de Carvalho, Leucio Câmara Alves, Rafael Antonio Nascimento Ramos

Abstract readReview
In one paragraph

Review in Veterinary research communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

José Atanásio de Oliveira NetoLaboratory of Parasitology, Federal University of the Agreste of Pernambuco, Garanhuns, 55292-278, Brazil.
Geovana Mergulhão da SilvaLaboratory of Parasitology, Federal University of the Agreste of Pernambuco, Garanhuns, 55292-278, Brazil.
Samuel Souza SilvaLaboratory of Parasitology, Federal University of the Agreste of Pernambuco, Garanhuns, 55292-278, Brazil.
Tatiene Rossana Móta SilvaLaboratory of Parasitology, Federal University of the Agreste of Pernambuco, Garanhuns, 55292-278, Brazil.
Gílcia Aparecida de CarvalhoLaboratory of Parasitology, Federal University of the Agreste of Pernambuco, Garanhuns, 55292-278, Brazil.
Leucio Câmara AlvesDepartment of Veterinary Medicine, Federal Rural University of Pernambuco, Recife, 52171-900, Brazil.
Rafael Antonio Nascimento RamosLaboratory of Parasitology, Federal University of the Agreste of Pernambuco, Garanhuns, 55292-278, Brazil. rafael.ramos@ufape.edu.br.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Trypanosoma cruzi (Kinetoplastea: Trypanosomatidae) is the etiological agent of American Trypanosomiasis (AT). Although knowledge of natural infection by T. cruzi in dogs has increased worldwide relatively few studies have evaluated this occurrence in Brazil, with much of the available information restricted to isolated case reports. The aim of this research was to provides a critical review of AT in dogs demonstrating the current distribution of cases in Brazil and to propose a diagnostic approach for veterinary clinicians. This review comprised a comprehensive search of scientific articles and case reports published, available at PubMed, Scielo and Google Scholar websites. A combination of keywords including “American Trypanosomiasis”, “Chagas disease”, “dogs”, “T. cruzi”, and “Brazil” was used for the search. Data from this review underscores the importance of dogs as domestic hosts of T. cruzi and provides the current distribution of this infection in these animals in Brazil. Additionally, it reveals important knowledge gaps regarding veterinarian awareness of T. cruzi and its diagnostic methods in small animal clinics. The diagnostic flowchart presented here serves to guide veterinarians to perform a proper diagnostic using currently available methods. The prevention of AT in dogs faces several challenges, including the domiciliation of triatomines and the misdiagnosis of cases. These factors contribute to the ongoing presence of untreated animals, which can serve as important sources of infection for triatomine vectors and ultimate risk of human infections. For the AT control, it is important to reinforce the necessity of a One Health approach and to underscore the role of veterinarians in this process. It is pivotal to focusing on diagnosing and treating humans and dogs, controlling vectors, and improving human dwellings, especially in rural areas. Finally, cases of AT in dogs in Brazil distribute heterogeneously in all five regions of the country, with a slight predominance in the Northeast region.

Indexed as

Chagas DiseaseDog DiseasesAnimalsBrazilDogsTrypanosoma cruziAmerican trypanosomiasisCanineEpidemiologyOne healthTrypanosoma cruzi

Identifiers

PMID41579267
PMCPMC12831677

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.