ReviewActa neurologica Belgica2026
Obsessive-compulsive disorder in people with multiple sclerosis: a systematic review and meta-analysis.
Review in Acta neurologica Belgica, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
0 citing papers in PubMed.
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Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMultiple sclerosis (MS) is a chronic, immune-mediated neurological disorder that is frequently associated with psychiatric comorbidities, particularly obsessive-compulsive disorder (OCD). OCD may increase psychological burden, reduce quality of life, and exacerbate disease activity in people with MS (PwMS). However, the frequency of OCD in PwMS and its association with MS remain mostly uncertain. This review aimed to estimate the overall prevalence of OCD in PwMS and to evaluate the association between MS and OCD.
methodsA comprehensive search of PubMed, Scopus, Embase, and Web of Science was conducted up to January 2025 to identify studies that assessed the frequency rate of OCD in PwMS or explored the relationship between MS and OCD. The meta-analysis was performed using a random-effects model in R version 4.4.0.
resultsTen studies on 1024 PwMS and 172 healthy controls met the inclusion criteria. The pooled prevalence of OCD among PwMS was 10.7% (95% CI: 5.6% to 15.9%, I
conclusionThis review indicated that the overall frequency 10.7% of OCD increased risk (3.2-fold) of OCD among PwMS. Screening and targeted interventions for OCD may enhance clinical outcomes and quality of life of PwMS.
Indexed as
Identifiers
41579245What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.