ArticleNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2026
The perception of disability in multiple sclerosis: validation and psychometric properties of the Italian perceived disability scale.
Article in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
introductionMultiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system and a leading cause of disability in young adults. Traditional measures of MS-related disability primarily rely on objective clinical evaluations, often neglecting patients' subjective experiences, which are affected by physical, cognitive, and emotional factors. This study aimed to validate the Italian Perceived Disability Scale (IPDS), a 20-item self-report tool designed to assess perceived disability across physical, psychological, and social domains.
methodsA cohort of 100 individuals with MS underwent the IPDS and a comprehensive clinical and neuropsychological assessment, including the Expanded Disability Status Scale (EDSS), Fatigue Severity Scale (FSS), Hamilton Depression and Anxiety Rating Scales (HAM-D and HAM-A), and the Brief Repeatable Battery of Neuropsychological Tests (BRB-N).
resultsFactor analysis confirmed the five-factor structure of the IPDS, accounting for 75% of the total variance, with excellent internal consistency (Cronbach's alpha = 0.90). The IPDS total score showed significant correlations with EDSS (r = 0.43, p < 0.001), FSS (r = 0.61, p < 0.001), HAM-A (r = 0.41, p < 0.001), and HAM-D (r = 0.48, p < 0.001).
conclusionsThese findings validate the IPDS as a reliable and valuable tool for assessing perceived disability in MS. By capturing patients'subjective experiences, the IPDS offers valuable insights for personalized care and supports the integration of patient-reported outcomes into routine clinical practice. Future research should investigate its sensitivity to longitudinal changes and its applicability across diverse MS populations.
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