Evidence map›Paper›PMID 41579157›Full record

ArticleNeuroradiology2026

Improving catheter navigation in neurointerventional procedures: single-center insights on next-generation steerable guidewires.

Om H Gandhi, Suraj R Dumasia, Sami Almasri, Nathan Yu, Erin N Walker, Linda Bagley, Omar A Choudhri

Abstract read
In one paragraph

Article in Neuroradiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Om H GandhiDepartment of Neurosurgery, University of Pennsylvania, Philadelphia, PA, USA.
Suraj R DumasiaDepartment of Neurosurgery, University of Pennsylvania, Philadelphia, PA, USA.
Sami AlmasriDepartment of Neurosurgery, University of Pennsylvania, Philadelphia, PA, USA.
Nathan YuDepartment of Neurosurgery, University of Pennsylvania, Philadelphia, PA, USA.
Erin N WalkerDepartment of Neurosurgery, University of Pennsylvania, Philadelphia, PA, USA.
Linda BagleyDepartment of Radiology, University of Pennsylvania, Philadelphia, PA, USA.
Omar A ChoudhriDepartment of Radiology, University of Pennsylvania, Philadelphia, PA, USA. Omar.Choudhri@pennmedicine.upenn.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeSteerable guidewires with deflectable tips enable real-time navigation through complex cerebrovascular anatomy without requiring wire removal and tip reshaping. Despite promising early reports, systematic clinical evaluation remains limited.

methodsWe conducted a retrospective analysis of 58 consecutive neurointerventional procedures utilizing steerable guidewires at two centers from September 2024 to August 2025. The cohort comprised 48 cases using the Drivewire 24 (DW24, 0.024-inch diameter) and 10 cases using the Artiria SmartGUIDE (0.014-inch diameter). Primary outcomes included technical success, safety profile, and operator assessment. We also performed a scoping literature review of all published steerable guidewire studies in neurointerventional applications.

resultsTechnical success in reaching target vessels was achieved in 100% of cases for both systems with no intraoperative or postoperative complications. Mean fluoroscopy time was 32.7 ± 29.5 min for DW24 and 26.1 ± 16.2 min for Artiria procedures. Treatment indications included aneurysm procedures (53.4%), diagnostic angiographies (20.7%), venous sinus stenting (13.8%), middle meningeal artery embolizations (8.6%), and stroke interventions (3.4%). 8.3% of procedures using DW24 were considered higher-risk by the primary operator without steerable capability, including successful navigation of complex posterior circulation anatomy in giant basilar aneurysms and recurrent superior cerebellar artery aneurysms with prior stent constructs. Our limited experience with the Artiria system (n = 10) revealed operator-noted challenges with shape retention. The scoping review identified only three prior studies encompassing 65 procedures, establishing this as the largest reported experience.

conclusionBoth steerable guidewire systems achieved perfect technical success with excellent safety profiles. Based on our preliminary experience, the DW24 appeared to offer advantages for procedures requiring navigating larger catheters through tortuous anatomy. These findings support selective clinical use of steerable guidewire technology in challenging neurointerventional procedures.

Indexed as

CathetersCerebrovascular DisordersEndovascular ProceduresAgedCerebral AngiographyEquipment DesignFemaleHumansIntracranial AneurysmMaleMiddle AgedRetrospective StudiesAneurysm treatmentCerebrovascular navigationNeurointerventionalSteerable guidewireStroke intervention

Identifiers

PMID41579157
PMCPMC13216097

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.