Evidence map›Paper›PMID 41579125›Full record

ArticleJACC. Case reports2026

Heart Block in Pregnancy From Parvovirus B19.

James Menting, Olivia Siefke, Karam Ayoub

Abstract readCase Reports
In one paragraph

Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

James MentingGill Heart & Vascular Institute, University of Kentucky, Lexington, Kentucky, USA. Electronic address: jlme264@uky.edu.
Olivia SiefkeGill Heart & Vascular Institute, University of Kentucky, Lexington, Kentucky, USA.
Karam AyoubGill Heart & Vascular Institute, University of Kentucky, Lexington, Kentucky, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundComplete heart block is a rare and possibly life-threatening condition in pregnancy, requiring timely recognition and multispecialty management. CASE SUMMARY: This case report describes a previously healthy pregnant woman who developed high-grade atrioventricular block due to a parvovirus B19 infection. Before her presentation, she had a upper respiratory infection with a "slapped cheek" rash, classic for parvovirus B19. Other cardiac, infectious, and rheumatologic etiologies were excluded. She had subsequent recovery of atrioventricular conduction with conservative management. DISCUSSION: Although congenital heart block is a known fetal complication of parvovirus B19, maternal cardiac conduction abnormalities linked to this virus have not previously been documented. Patients with heart block during pregnancy should be managed similarly to those who are not pregnant; however, caution should be exercised when using fluoroscopy for pacemaker placement. TAKE-HOME MESSAGE: This case highlights the importance of a broad differential diagnosis, a multidisciplinary approach, and appropriate maternal-fetal risk stratification in the management of cardiac arrhythmias during pregnancy.

Indexed as

bradycardiacardiomyopathydyspneaechocardiographyelectrophysiologypregnancyultrasound

Identifiers

PMID41579125
PMCPMC13002523

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.