Evidence map›Paper›PMID 41579021›Full record

ArticleScandinavian journal of medicine & science in sports2026

Low-Load Blood Flow Restriction Training Enhances Brachial Blood Flow During Exercise but not Reactive Hyperemia in Experienced Climbers.

Titouan Paul Perrin, Hugo Randy, Pyrène Santal, Xavier Hugues, Nicolas Tourette, Marie Coudurier, Michel Guinot, Violaine Cahouet, Franck Quaine, Stéphane Doutreleau and 5 more

Abstract read
In one paragraph

Article in Scandinavian journal of medicine & science in sports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Titouan Paul PerrinInserm, CHU Grenoble Alpes, HP2, Univ. Grenoble Alpes, Grenoble, France.ORCID https://orcid.org/0000-0001-8862-8641
Hugo RandyInserm, CHU Grenoble Alpes, HP2, Univ. Grenoble Alpes, Grenoble, France.
Pyrène SantalInserm, CHU Grenoble Alpes, HP2, Univ. Grenoble Alpes, Grenoble, France.
Xavier HuguesCNRS, Grenoble INP, GIPSA-Lab, Univ. Grenoble Alpes, Grenoble, France.ORCID https://orcid.org/0000-0001-6642-2845
Nicolas TouretteInserm, CHU Grenoble Alpes, HP2, Univ. Grenoble Alpes, Grenoble, France.ORCID https://orcid.org/0009-0004-6886-2704
Marie CoudurierInserm, CHU Grenoble Alpes, HP2, Univ. Grenoble Alpes, Grenoble, France.
Michel GuinotInserm, CHU Grenoble Alpes, HP2, Univ. Grenoble Alpes, Grenoble, France.ORCID https://orcid.org/0000-0002-2128-5469
Violaine CahouetCNRS, Grenoble INP, GIPSA-Lab, Univ. Grenoble Alpes, Grenoble, France.
Franck QuaineCNRS, Grenoble INP, GIPSA-Lab, Univ. Grenoble Alpes, Grenoble, France.
Stéphane DoutreleauInserm, CHU Grenoble Alpes, HP2, Univ. Grenoble Alpes, Grenoble, France.
Samuel VergèsInserm, CHU Grenoble Alpes, HP2, Univ. Grenoble Alpes, Grenoble, France.
Laurent VigourouxCNRS, ISM, Univ Aix-Marseille, Marseille, France.
Hugo KerherveM2S laboratory, Univ Rennes, Rennes, France.
Mathieu MarillierInserm, CHU Grenoble Alpes, HP2, Univ. Grenoble Alpes, Grenoble, France.
Julien Vincent BrugniauxInserm, CHU Grenoble Alpes, HP2, Univ. Grenoble Alpes, Grenoble, France.

Funding

Agence Nationale de la Recherche
6 · The paper itself

Abstract

Low-load blood flow restriction training (LLBFRT) induces significant vascular stress, which is often associated with vascular remodeling, increased capillarization and muscle blood flow. These adaptations may be of interest to climbers as their endurance performance is limited by blood supply due to the isometric and intermittent nature of finger flexors (FD) contraction. This study, thus, aimed to assess vascular adaptations to a 5-week FD protocol using LLBFRT (n = 12, cuff pressure = 60% of the limb occlusion pressure) and compare these responses to those elicited by high-load resistance training (HLRT, n = 12) and no specific training (CON, n = 12) in male climbers. Participants in LLBFRT and HLRT trained twice a week, respectively at ~40% and ~75% of maximal voluntary contraction (MVC). Before and after the intervention, flow-mediated dilation (FMD), peak reactive hyperemia blood flow, brachial blood flow and muscle oxygenation (near-infrared spectroscopy) at rest and during contractions from 10% to 60% MVC were assessed using brachial doppler-ultrasound. Brachial blood flow across contraction intensities was significantly improved in LLBFRT (+19% ± 31%; p = 0.011, d = 0.5) but not in CON and HLRT. Oxy- and total hemoglobin concentrations decreased less during contraction following LLBFRT while did not change following CON and HLRT. Reactive hyperemia and FMD were not altered by any training modality. In conclusion, despite no difference with HLRT, LLBFRT was the only protocol which increased significantly blood flow of the feeding artery and O

Indexed as

Brachial ArteryExerciseHyperemiaMountaineeringMuscle, SkeletalRegional Blood FlowResistance TrainingAdaptation, PhysiologicalAdultFingersHumansMaleMuscle ContractionOxygen ConsumptionSpectroscopy, Near-InfraredUltrasonography, Dopplerblood flow restriction trainingflow‐mediated dilationnear‐infrared spectroscopypeak reactive hyperemiaregional blood flowrock‐climbing

Identifiers

PMID41579021
PMCPMC12831503

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.