ArticleMedicina oral, patologia oral y cirugia bucal2026
Lesion shrinkage and tooth preservation-based optimal timing for definitive surgery following marsupialization of cystic odontogenic jaw lesions.
Article in Medicina oral, patologia oral y cirugia bucal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundThis study aimed to investigate the appropriate timing for the second enucleation surgery to remove entire cystic odontogenic jaw lesions based on tooth preservation and lesion shrinkage patterns after the marsupialization of jaw lesions. MATERIAL AND
methodsThis retrospective study included 20 patients who underwent marsupialization between January 2013 and December 2024. Changes in the number of lesions affecting the teeth before and after marsupialization were investigated, and two-dimensional lesion size changes on panoramic radiographs and three-dimensional volume changes on computed tomography images over time were measured and analyzed. Statistical analysis was performed using the Mann-Whitney test for non-normally distributed, continuous variables and the chi-square test or Fisher's exact test for nominal variables, as appropriate, with a significance level of p<0.05.
resultsAfter an average of 62.51±31.17 weeks of marsupialization, the number of lesion-involved teeth decreased by 46.48%. An average lesion reduction of 50.85±14.95% and 62.86±17.25% (p<0.05) in two- and three-dimensional volumetric assessments was observed. Lesion shrinkage was the most significant between 16 and 24 weeks (95% confidence interval), with a mean of 18±10 weeks.
conclusionsDefinitive enucleation surgery should be delayed by 24 weeks to maximize neo-bone formation in the cystic odontogenic jaw lesion cavity and maintain the vitality of the affected teeth.
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