Trial reportMedicina oral, patologia oral y cirugia bucal2026
Role of articaine and perineural dexamethasone in prolonging postoperative analgesia in mandibular third molar surgery: A comparative analysis.
Trial report in Medicina oral, patologia oral y cirugia bucal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPain management in dentistry, particularly in procedures such as mandibular third molar surgery, poses a significant challenge due to the transient efficacy of traditional local anesthetics. To address this, adjunctive therapies such as dexamethasone have been explored to prolong anesthesia and alleviate postoperative pain. However, the efficacy and safety of this approach in mandibular third molar surgery remain underexplored. MATERIAL AND
methodsThis study assessed the efficacy and safety of combining articaine with perineural dexamethasone for inferior alveolar nerve block in patients undergoing mandibular third molar extraction. Sixty patients aged 18-35 years were enrolled and randomly assigned to three groups receiving different anesthesia protocols. Anesthesia duration, postoperative pain scores, and adverse events were evaluated.
resultsThe incorporation of dexamethasone into articaine-based anesthesia significantly prolonged the duration of analgesia compared to articaine alone, underscoring its potential as an effective adjunctive therapy. While no significant differences were observed in the duration of operation, analgesic consumption, or incidence of adverse events among the groups, trends favoring the articaine-dexamethasone cohorts were noted in postoperative pain scores.
conclusionsCombining articaine with perineural dexamethasone for inferior alveolar nerve block prolongs postoperative analgesia in mandibular third molar surgery. While additional research using larger sample sizes and longer follow-up durations is needed, these findings imply that this combination could be beneficial for improving pain management during oral surgery.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.