Evidence map›Paper›PMID 41578861›Full record

ArticleAesthetic surgery journal2026

Short-term Outcomes of Polydioxanone Synthetic Mesh in 2-stage Breast Reconstruction: A Single-Center Comparative Study.

Erin N Abbott, Ruoying Li, Daniella King, Paulina E Chumakov, Elianna Dash, Carrie A Kubiak, Stephane A Braun, Allen Gabriel, Megan Vucovich, Lauren M Mioton and 1 more

Abstract readComparative Study
In one paragraph

Article in Aesthetic surgery journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ruoying Li
Daniella King
Paulina E Chumakov
Elianna Dash
Carrie A Kubiak
Stephane A Braun
Allen Gabriel
Megan Vucovich
Lauren M Mioton

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPolydioxanone (PDO) mesh offers a more cost-effective option than biologic mesh for soft tissue support for 2-stage breast reconstruction with tissue expansion but differences in complication rates have not been well established.

objectivesThe purpose of this study was to present the early postoperative complications recorded by a single center following immediate tissue expander (TE) insertion for breast reconstruction using PDO mesh, biologic mesh, or no mesh.

methodsA retrospective cohort study was performed of patients undergoing immediate TE insertion following mastectomy over a 3-year period (2021-2024) at a single academic center. Patients were grouped by mesh type. Univariate and multivariate regression analyses were performed.

resultsA total of 919 TEs in 524 patients were analyzed: 27.7% with PDO mesh, 52.9% with biologic mesh, and 19.5% with no mesh. TE infection occurred in 70 breasts (7.6%) in 55 patients (10.5%), with infection rates of 10.6% in the PDO mesh group, 6.6% in the biologic mesh group, and 6.2% in the no mesh group (P = NS). Ipsilateral radiation exposure was the only factor significantly associated with infection (odds ratio, 7.2; P = .008). Prepectoral reconstructions resulted in higher infection rates than subpectoral cases, but mesh type was not independently associated with infection. Explantation occurred in 120 breasts (13.0%) with no difference between mesh types.

conclusionsShort-term outcomes following TE placement were comparable among patients receiving PDO mesh, biologic mesh, or no mesh. These findings suggest that mastectomy flap quality and patient factors may have a greater impact on complications than mesh type, especially with prepectoral placement. LEVEL OF EVIDENCE: 3 (THERAPEUTIC): For image description, please refer to the figure legend and surrounding text.

Indexed as

MammaplastyPolydioxanonePostoperative ComplicationsSurgical MeshTissue ExpansionAdultAgedBreast NeoplasmsFemaleHumansMastectomyMiddle AgedRetrospective StudiesSurgical Wound InfectionTime FactorsTissue Expansion DevicesPolydioxanone

Identifiers

PMID41578861
PMCPMC13577730

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.