ArticleThe Eurasian journal of medicine2026
Optical Coherence Tomography Angiography-Based Evaluation of Foveal Avascular Zone and Macular Vessel Density in Prediabetic Patients.
Article in The Eurasian journal of medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Early Retinal Microvascular Alterations in Prediabetes and Diabetes Without Clinically Detectable Retinopathy.The Eurasian journal of medicine · 2026Article
Corrections and comments
- Erratum issuedErratum.2026
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo assess macular layer thickness, macular vessel density, and foveal avascular zone (FAZ) parameters in prediabetic patients compared with healthy normoglycemic controls using optical coherence tomography angiography (OCTA).
methodsThirty prediabetic patients (group A; fasting plasma glucose 100-125 mg/dL, postprandial plasma glucose 140-199 mg/dL, glycated hemoglobin 5.7%-6.4%) and 30 age-matched normoglycemic subjects (group B) were included. The OCTA imaging was used to evaluate superficial capillary plexus (SCP) and deep capillary plexus (DCP) vessel densities, as well as FAZ area and perimeter. Participants with poor image quality, high refractive error, glaucoma, prior intraocular surgery, chorioretinal atrophy, or other ocular/systemic comorbidities were excluded.
resultsThe SCP and DCP perfusion densities (PDs) were lower in the prediabetic group, with significant reductions in the inferior and temporal quadrants of the DCP and the temporal quadrant of the SCP (P < .05). The FAZ area and perimeter were larger in the prediabetic group but not statistically significant (P > .05). Macular thickness was greater in all quadrants in group A, with significant thickening in the nasal and inferior quadrants (P < .05).
conclusionPrediabetic patients demonstrated early microvascular and structural changes, including reduced macular PD, increased macular thickness, and FAZ enlargement. These findings suggest subclinical retinal involvement in prediabetes, warranting larger longitudinal studies. Cite this article as: Utlu B, Utlu ES, Çinici E, Akgöz H, Bayrakçeken K, Kozan BD. Optical coherence tomography angiography-based evaluation of foveal avascular zone and macular vessel density in prediabetic patients. Eurasian J Med. 2026, 58 (1),1165, doi:10.5152/eurasianjmed.2026.261165.
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