Evidence map›Paper›PMID 41578795›Full record

Trial reportThe Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology2025

Diagnostic Performance of Linked Color Imaging Compared to White Light Imaging During Secondary Endoscopic Evaluation in Patients with Gastric Neoplasia Referred for Endoscopic Resection: A Randomized Comparative Study.

Jae Gon Lee, In Kyung Yoo, Sang Pyo Lee

Abstract readRandomized Controlled TrialComparative Study
In one paragraph

Trial report in The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jae Gon LeeDepartment of Internal Medicine, Hanyang University Guri Hospital, Hanyang University College of Medicine, Guri, Korea.
In Kyung YooDepartment of Internal Medicine, CHA Bundang Medical Center, CHA University, Seongnam, Korea.
Sang Pyo LeeDepartment of Internal Medicine, Hanyang University College of Medicine, Seoul, Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimsLinked color imaging (LCI) has been shown to improve the visibility of gastric lesions and may enhance the detection of gastric superficial neoplasia (GSN). The aim was to compare the detection performance of LCI versus white light imaging (WLI) in patients referred for endoscopic resection of GSNs. MATERIALS AND

methodsIn this randomized prospective comparative study, patients who were referred for endoscopic resection of gastric adenoma or early gastric cancer (ECG) were assigned to either the LCI or WLI group. Initial endoscopic evaluation was performed using the assigned mode (LCI or WLI), followed by a second examination using the alternate mode. The primary outcome was detection sensitivity for GSNs.

resultsNinety-five patients with 104 lesions were analyzed: 48 in the LCI group and 47 in the WLI group. Detection sensitivity at first observation was 94.23% in the LCI group and 86.54% in the WLI group (P = .122). The mean tumor detection time was significantly shorter in the LCI group (54.2 ± 38.4 seconds) than in the WLI group (74.0 ± 55.5 seconds; P = .049). Tumors with type IIb morphology were significantly more likely to be missed than tumors with other morphologies (P = .014).

conclusionLinked color imaging may improve lesion detection performance and efficiency during the endoscopic evaluation of GSNs.   Cite this article as: Lee JG, Yoo IK, Lee SP, et al. Diagnostic performance of linked color imaging compared to white light imaging during secondary endoscopic evaluation in patients with gastric neoplasia referred for endoscopic resection: A randomized comparative study. Turk J Gastroenterol. 2026;37(1):44-54.

Indexed as

AdenomaGastroscopyStomach NeoplasmsAdultAgedColorFemaleHumansLightMaleMiddle AgedProspective StudiesSensitivity and Specificity

Identifiers

PMID41578795
PMCPMC12824881

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.